THE EFFECT OF PROBIOTIC SUPPLEMENTATIONS ON COGNITIVE FUNCTION IN PATIENTS WITH PRIMARY AND SECONDARY ALZHEIMER

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Agahi Azadeh; HAMIDI GHOLAMALI; SALAMI MAHMOUD; Alinaghipour Azam; DANESHVAR KAKHAKI REZA; SOHEILI MASOUD

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2018 | Volume:20 | Issue:12 (129) Page(s): 1-9

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Title

THE EFFECT OF PROBIOTIC SUPPLEMENTATIONS ON COGNITIVE FUNCTION IN PATIENTS WITH PRIMARY AND SECONDARY ALZHEIMER

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Keywords

ALZHEIMERQ1

COGNITIVE FUNCTIONQ1

PROBIOTICQ2

Abstract

Background: ALZHEIMER’s disease (AD) is a most common neurodegenerative disorder. The aim of this study was to investigate the effect of PROBIOTIC on COGNITIVE FUNCTION in patients with ALZHEIMER disease.Materials and Methods: This clinical trial was conducted among 48 AD patients. The patients were randomly divided into two groups (n=23 in control group and n=25 in PROBIOTIC group) treating with capsules 500mg containing maltodextrine (control group) and PROBIOTIC supplementation (probiotic group) for 12 weeks. Mini-mental state examination (MMSE) and TYM test score was recorded in all subjects before and after treatment.Results: After 12 weeks intervention, compared with the control group, the PROBIOTIC treated, patients with mild degree of ALZHEIMER disease showed an improvement in the MMSE, TYM score (p<0.0001).Conclusion: Our current study demonstrated that PROBIOTIC consumption for 12 weeks positively affects COGNITIVE FUNCTION in mild degree of AD.

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APA: Copy

Agahi, Azadeh, HAMIDI, GHOLAMALI, SALAMI, MAHMOUD, Alinaghipour, Azam, DANESHVAR KAKHAKI, REZA, & SOHEILI, MASOUD. (2018). THE EFFECT OF PROBIOTIC SUPPLEMENTATIONS ON COGNITIVE FUNCTION IN PATIENTS WITH PRIMARY AND SECONDARY ALZHEIMER. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 20(12 (129) ), 1-9. SID. https://sid.ir/paper/69794/en

Vancouver: Copy

Agahi Azadeh, HAMIDI GHOLAMALI, SALAMI MAHMOUD, Alinaghipour Azam, DANESHVAR KAKHAKI REZA, SOHEILI MASOUD. THE EFFECT OF PROBIOTIC SUPPLEMENTATIONS ON COGNITIVE FUNCTION IN PATIENTS WITH PRIMARY AND SECONDARY ALZHEIMER. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2018;20(12 (129) ):1-9. Available from: https://sid.ir/paper/69794/en

IEEE: Copy

Azadeh Agahi, GHOLAMALI HAMIDI, MAHMOUD SALAMI, Azam Alinaghipour, REZA DANESHVAR KAKHAKI, and MASOUD SOHEILI, “THE EFFECT OF PROBIOTIC SUPPLEMENTATIONS ON COGNITIVE FUNCTION IN PATIENTS WITH PRIMARY AND SECONDARY ALZHEIMER,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 20, no. 12 (129) , pp. 1–9, 2018, [Online]. Available: https://sid.ir/paper/69794/en

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