مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Antioxidant and Antidiabetic Effect of Capparis decidua Edgew (Forssk. ) Extract on Liver and Pancreas of Streptozotocin-induced Diabetic Rats

Pages

  76-82

Abstract

 Introduction: The twig of Capparis decidua has been traditionally used as an antidiabetic agent but its medicinal use has not been scientifically proved yet. The present study evaluated the antidiabetic effect and antioxidant activities of aquatic extract of twig of C. decidua on the Liver and Pancreas of diabetic rats induced by streptozotocin (STZ). Materials and Methods: The effect of Capparis decidua was evaluated by biochemical, histological and Fourier-transform Infrared Spectroscopy (FTIR) studies. All biochemical and biophysical parameters were estimated after 15 days of daily oral administrations of the aqueous extract. Results: Findings showed that oral use of C. decidua extract (250 mg/kg) caused significant reduction in the fasting blood glucose levels in diabetic rats when compared to the control rats. Moreover, the altered level of lipid peroxidation, antioxidant, lipid profiles, Liver enzymes, and also structural changes were reversed in STZ-induced diabetic rats which received C. decidua extract. Conclusions: In conclusion, aqueous extract of C. decidua has potent antidiabetic and antioxidant activity.

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    APA: Copy

    Ramzani Ghara, Abdollah, Ezzati Ghadi, Fereshteh, HOSSEINI, SEYED HAMZEH, Piacente, Sonia, Cerulli, Antonietta, ALIZADEH, AKRAM, & MIRMAHMOUDI, ROUHOLLAH. (2021). Antioxidant and Antidiabetic Effect of Capparis decidua Edgew (Forssk. ) Extract on Liver and Pancreas of Streptozotocin-induced Diabetic Rats. JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS, 8(1), 76-82. SID. https://sid.ir/paper/698142/en

    Vancouver: Copy

    Ramzani Ghara Abdollah, Ezzati Ghadi Fereshteh, HOSSEINI SEYED HAMZEH, Piacente Sonia, Cerulli Antonietta, ALIZADEH AKRAM, MIRMAHMOUDI ROUHOLLAH. Antioxidant and Antidiabetic Effect of Capparis decidua Edgew (Forssk. ) Extract on Liver and Pancreas of Streptozotocin-induced Diabetic Rats. JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS[Internet]. 2021;8(1):76-82. Available from: https://sid.ir/paper/698142/en

    IEEE: Copy

    Abdollah Ramzani Ghara, Fereshteh Ezzati Ghadi, SEYED HAMZEH HOSSEINI, Sonia Piacente, Antonietta Cerulli, AKRAM ALIZADEH, and ROUHOLLAH MIRMAHMOUDI, “Antioxidant and Antidiabetic Effect of Capparis decidua Edgew (Forssk. ) Extract on Liver and Pancreas of Streptozotocin-induced Diabetic Rats,” JOURNAL OF APPLIED BIOTECHNOLOGY REPORTS, vol. 8, no. 1, pp. 76–82, 2021, [Online]. Available: https://sid.ir/paper/698142/en

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