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Title

Human Rhinovirus Molecular Epidemiology and Genotyping in Iranian Military Trainees with Acute Respiratory Symptoms

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Abstract

 Background: Human Rhinovirus (HRV) is still the most prevalent viral infection in humans and a significant cause of acute Respiratory Tract Infections (ARTIs) in many communities, including military personnel undergoing basic training. Objectives: In this research, we assessed the molecular epidemiology, Genotyping, and phylogenetic classification of HRVs in Iranian Military Trainees with respiratory infections (RI). Methods: For HRV identification and Genotyping, respiratory specimens were obtained, and RT-PCR was conducted for Genotyping and phylogenetic analysis of HRV utilizing primers for the 5-UTR region. Results: Among 400 Iranian Military Trainees (average age of 21 4 years, the range of 18-57 years) with respiratory infections, HRV was detected in 29 patients (7%) using RT-PCR. The direct sequencing of PCR products from 10 specimens showed that the incidence of type A (n = 5, 50%) was higher than that of type B (n = 4, 40%) and type C (n = 1, 10%). There were no significant associations between HRV and respiratory and clinical symptoms, blood group, and indoor or outdoor conditions (P-value > 0. 05). Conclusions: This researchwasthe first to recordHRVas a significant cause of respiratory problemsamongMilitary Trainees in Iran, with a frequency of 7%. The most prevalent genotype was HRV-A, which may be applicable in epidemiological and clinical studies, as well as vaccination plans.

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    APA: Copy

    SAFARNEZHAD TAMESHKEL, FAHIMEH, Salimi Jeda, Ali, TAVAKOLI, AHMAD, KARBALAIE NIYA, MOHAMMAD HADI, IZADI, MORTEZA, ZAMANI, FARHAD, & KEYVANI, HOSSEIN. (2020). Human Rhinovirus Molecular Epidemiology and Genotyping in Iranian Military Trainees with Acute Respiratory Symptoms. JOURNAL OF ARCHIVES IN MILITARY MEDICINE, 8(4), 0-0. SID. https://sid.ir/paper/698556/en

    Vancouver: Copy

    SAFARNEZHAD TAMESHKEL FAHIMEH, Salimi Jeda Ali, TAVAKOLI AHMAD, KARBALAIE NIYA MOHAMMAD HADI, IZADI MORTEZA, ZAMANI FARHAD, KEYVANI HOSSEIN. Human Rhinovirus Molecular Epidemiology and Genotyping in Iranian Military Trainees with Acute Respiratory Symptoms. JOURNAL OF ARCHIVES IN MILITARY MEDICINE[Internet]. 2020;8(4):0-0. Available from: https://sid.ir/paper/698556/en

    IEEE: Copy

    FAHIMEH SAFARNEZHAD TAMESHKEL, Ali Salimi Jeda, AHMAD TAVAKOLI, MOHAMMAD HADI KARBALAIE NIYA, MORTEZA IZADI, FARHAD ZAMANI, and HOSSEIN KEYVANI, “Human Rhinovirus Molecular Epidemiology and Genotyping in Iranian Military Trainees with Acute Respiratory Symptoms,” JOURNAL OF ARCHIVES IN MILITARY MEDICINE, vol. 8, no. 4, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/698556/en

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