The Effect of Aerobic-resistance Training on Plasma Levels of bFGF in Coronary Artery Disease After CABG

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Hamidi Azar; RASHIDLAMIR AMIR; KHAJEI RAMBOD; ZAREI MEHDI; ZENDEDEL AHMAD

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Journal Paper

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Journal: Journal of Arak University Medical Sciences Year:2020 | Volume:23 | Issue:3 (145) Page(s): 314-316

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Information Journal Paper

Title

The Effect of Aerobic-resistance Training on Plasma Levels of bFGF in Coronary Artery Disease After CABG

Author(s)

Keywords

Cardiac rehabilitation

Aerobic-resistance training

bFGF

CABG

Abstract

Background and Aim Coronary Heart Disease (CAD) is one of the most important causes of mortality. Exercise activities after coronary artery bypass surgery increase the density of myocardial capillaries called angiogenesis and improve cardiovascular function. The aim of the present study was to determine the effect of Aerobic-resistance training on plasma basic fibroblast grown factor levels in post-coronary artery bypass grafting patients. Methods & Materials The sample consisted of 30 men aged 45-60 years who underwent bypass surgery. They were randomly divided into experimental (n=15) and control (n=15) groups. The experimental group performed aerobic resistance training for eight weeks (3 sessions per week) and the control group did not. Blood samples were taken 24 hours before the start of the first training session and 48 hours after the last training session while all subjects were fasting. In vitro ELISA method was used to measure bFGF. Independent and paired t-test and Shapiro-Wilk test were used to analyze the data at the significant level of 0. 05 in SPSS v. 21. Ethical Considerations This study was registered (Ethics Code: IR. IAU. NEYSHABUR. REC. 1398. 01) in the Ethics Committee of Islamic Azad University, Neishabour Branch, and with Clinical Trial Code: IRCTID: IRCT20191228045919N1. Results Eight weeks of Aerobic-resistance training significantly increased bFGF levels in the exercise group compared to the control group (P=0. 002). Also, pre and post changes in the experimental group showed a significant increase in plasma bFGF levels (P=0. 002), which was not significant in the control group (P=0. 758). Conclusion According to the results, it may be concluded that combined (aerobic resistance) exercise may increase angiogenesis and capillary density in post-CABG patients by increasing plasma bFGF levels.

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APA: Copy

Hamidi, Azar, RASHIDLAMIR, AMIR, KHAJEI, RAMBOD, ZAREI, MEHDI, & ZENDEDEL, AHMAD. (2020). The Effect of Aerobic-resistance Training on Plasma Levels of bFGF in Coronary Artery Disease After CABG. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 23(3 (145) ), 314-316. SID. https://sid.ir/paper/703298/en

Vancouver: Copy

Hamidi Azar, RASHIDLAMIR AMIR, KHAJEI RAMBOD, ZAREI MEHDI, ZENDEDEL AHMAD. The Effect of Aerobic-resistance Training on Plasma Levels of bFGF in Coronary Artery Disease After CABG. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2020;23(3 (145) ):314-316. Available from: https://sid.ir/paper/703298/en

IEEE: Copy

Azar Hamidi, AMIR RASHIDLAMIR, RAMBOD KHAJEI, MEHDI ZAREI, and AHMAD ZENDEDEL, “The Effect of Aerobic-resistance Training on Plasma Levels of bFGF in Coronary Artery Disease After CABG,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 23, no. 3 (145) , pp. 314–316, 2020, [Online]. Available: https://sid.ir/paper/703298/en

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