EFFECT OF 1% PHENYTOINMUCO-ADHESIVE PASTE ON IMPROVEMENT OF PERIODONTAL STATUS IN PATIENTS WITH CHRONIC PERIODONTITIS: A RANDOMIZED BLINDED CONTROLLED CLINICAL STUDY

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RASHIDI MAYBODI FAHIMEH; HAERIAN ARDAKANI AHMAD; NABI MAYBODI MOHSEN; NASRABADI NAHID

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Journal Paper

Paper Information

Journal: JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES) Year:2016 | Volume:17 | Issue:3 Page(s): 256-261

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Title

EFFECT OF 1% PHENYTOINMUCO-ADHESIVE PASTE ON IMPROVEMENT OF PERIODONTAL STATUS IN PATIENTS WITH CHRONIC PERIODONTITIS: A RANDOMIZED BLINDED CONTROLLED CLINICAL STUDY

Author(s)

RASHIDI MAYBODI FAHIMEH | HAERIAN ARDAKANI AHMAD | NABI MAYBODI MOHSEN | NASRABADI NAHID | Issue Writer Certificate

Keywords

PHENYTOIN

CHRONIC PERIODONTITIS

MUCOADHESIVE PASTE

WOUND HEALING

Abstract

Statement of the Problem: PHENYTOIN (PHT) has been known to promote WOUND HEALING in some medical conditions owing to its proliferative as well as antiinflammatory effects. Yet, its application in oral lesions was less investigated.Purpose: The aim of this study was to evaluate changes in periodontal indices following the topical use of PHENYTOIN in CHRONIC PERIODONTITIS.Materials and Method: In this doubled-blind, randomized, split-mouth controlled clinical study, 20 patients with moderate to severe CHRONIC PERIODONTITIS referred to Periodontology Department of Shahid Sadoughi Medical University of Yazd in 2014 were selected consecutively. After initial therapy (scaling and root planning and oral hygiene instructions), periodontal indices including bleeding on probing (BOP), periodontal pocket depth (PPD) and modified gingival index (MGI) were recorded. Gingival facial surface of two posterior sextants with at least two teeth with similar conditions, were selected randomly. Then one surface received PHT paste whereas the other side had placebo as control. Patients were received the MUCOADHESIVE PASTEs under strict control by an examiner, twice a day for a week. Periodontal indices were measured 3 weeks after treatment. Data was analyzed with t-test and paired t-test by using SPSS 21 software.Results: It was observed that periodontal pocket depth was significantly more decreased in PHENYTOIN side in comparison with placebo one (p<0.05). In addition, inflammatory indices including bleeding on probing and modified gingival index declined more in the PHENYTOIN group (p=0.001 and p<0.05 respectively).Conclusion: These encouraging results support the use of 1% PHENYTOIN MUCOADHESIVE PASTE as an adjunctive in periodontal treatment.

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APA: Copy

RASHIDI MAYBODI, FAHIMEH, HAERIAN ARDAKANI, AHMAD, NABI MAYBODI, MOHSEN, & NASRABADI, NAHID. (2016). EFFECT OF 1% PHENYTOINMUCO-ADHESIVE PASTE ON IMPROVEMENT OF PERIODONTAL STATUS IN PATIENTS WITH CHRONIC PERIODONTITIS: A RANDOMIZED BLINDED CONTROLLED CLINICAL STUDY. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), 17(3), 256-261. SID. https://sid.ir/paper/703378/en

Vancouver: Copy

RASHIDI MAYBODI FAHIMEH, HAERIAN ARDAKANI AHMAD, NABI MAYBODI MOHSEN, NASRABADI NAHID. EFFECT OF 1% PHENYTOINMUCO-ADHESIVE PASTE ON IMPROVEMENT OF PERIODONTAL STATUS IN PATIENTS WITH CHRONIC PERIODONTITIS: A RANDOMIZED BLINDED CONTROLLED CLINICAL STUDY. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2016;17(3):256-261. Available from: https://sid.ir/paper/703378/en

IEEE: Copy

FAHIMEH RASHIDI MAYBODI, AHMAD HAERIAN ARDAKANI, MOHSEN NABI MAYBODI, and NAHID NASRABADI, “EFFECT OF 1% PHENYTOINMUCO-ADHESIVE PASTE ON IMPROVEMENT OF PERIODONTAL STATUS IN PATIENTS WITH CHRONIC PERIODONTITIS: A RANDOMIZED BLINDED CONTROLLED CLINICAL STUDY,” JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), vol. 17, no. 3, pp. 256–261, 2016, [Online]. Available: https://sid.ir/paper/703378/en

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