Role of Diffusion Tensor Imaging in Parkinson's Disease Diagnosis

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Hosseini Elahe; ASHRAFI FARZAD; FAEGHI FARIBORZ; HEKMATNIA ALI

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Journal Paper

Paper Information

Journal: Archives of Neuroscience Year:2021 | Volume:8 | Issue:2 Page(s): 0-0

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Title

Role of Diffusion Tensor Imaging in Parkinson's Disease Diagnosis

Author(s)

Hosseini Elahe | ASHRAFI FARZAD | FAEGHI FARIBORZ | HEKMATNIA ALI | Issue Writer Certificate

Keywords

Parkinson Disease

Diffusion Tensor Imaging

Magnetic Resonance Imaging

Fractional Anisotropy

Mean Diffusivity

Abstract

Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disease that affects the dopamine-containing neurons. In this study, the role of the Diffusion Tensor Imaging (DTI) method was investigated in the detection of PD. Objectives: The purpose of this study was to investigate the microstructural damage of the brain's white matter in PD using a non-invasive DTI technique. Methods: Twenty patients with PD were studied with comprehensive clinical assessments and DTI data. Also, 10 normal subjects were investigated. Fractional anisotropic (FA) and Mean Diffusivity (MD) values were calculated by drawing region of interest (ROI) on eight distinctive areas of the brain. Results: The level of FA and MD in substantia nigra (SN) was significantly different between the PD and healthy control (HC) groups. Also, differences were found in DTI parameters between PD and HC groups in some regions, such as genu, anterior limb of internal capsule (ALIC), splenium, and putamen. Conclusions: To summarize, DTI as a non-invasive method can be useful in the detection of Parkinson's disease.

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APA: Copy

Hosseini, Elahe, ASHRAFI, FARZAD, FAEGHI, FARIBORZ, & HEKMATNIA, ALI. (2021). Role of Diffusion Tensor Imaging in Parkinson's Disease Diagnosis. ARCHIVES OF NEUROSCIENCE, 8(2), 0-0. SID. https://sid.ir/paper/704196/en

Vancouver: Copy

Hosseini Elahe, ASHRAFI FARZAD, FAEGHI FARIBORZ, HEKMATNIA ALI. Role of Diffusion Tensor Imaging in Parkinson's Disease Diagnosis. ARCHIVES OF NEUROSCIENCE[Internet]. 2021;8(2):0-0. Available from: https://sid.ir/paper/704196/en

IEEE: Copy

Elahe Hosseini, FARZAD ASHRAFI, FARIBORZ FAEGHI, and ALI HEKMATNIA, “Role of Diffusion Tensor Imaging in Parkinson's Disease Diagnosis,” ARCHIVES OF NEUROSCIENCE, vol. 8, no. 2, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/704196/en

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