COMPARING THE FREQUENCY OF β-LACTAMASE ENZYME EXISTENCE IN ISOLATED NOSOCOMIAL INFECTION BACTERIA

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JALALPOUR SH.; KASRA KERMANSHAHI R.; NOUHI ASHRAF ALSADAT; ZARKESH ESFAHANI S.H.; ABOUSAEIDI H.

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Journal: JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES Year:2009 | Volume:8 | Issue:3 (32) Page(s): 203-214

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Title

COMPARING THE FREQUENCY OF β-LACTAMASE ENZYME EXISTENCE IN ISOLATED NOSOCOMIAL INFECTION BACTERIA

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Keywords

β–LACTAMASEQ3

β–LACTAME ANTIBIOTICSQ3

ANTIBIOTIC RESISTANCEQ2

PATHOGEN BACTERIAQ2

NOSOCOMIAL INFECTIONSQ2

Abstract

Background and Objectives: b-lactame antibiotics are very important in the cure of diseases. b-lactamase as a virulence agent causes resistance to these antibiotics. Existence of b-lactamase in the PATHOGEN BACTERIA can cause delay in the treatment. The aim of this research was to compare the frequency of b-lactamase enzyme existence in different types of isolated nosocomial infection bacteria in Alzahra hospital, Isfahan, Iran. Materials and Methods: This laboratory study was performed in Alzahra hospital of Isfahan in 2005-2006. According to sample size estimation, 100 infection samples (blood, urine, skin) were randomly selected. Identification of bacteria was performed using microbiological methods; such as: staining, chemical test, and use of differential and selective media. To determine b–lactamase production in bacteria, acidimetric method was used. Data was analyzed using descriptive statistics. Results: From the 100 isolated PATHOGEN BACTERIAs, 68.45% produced b-lactamase; 83.33% produced Staphylococcus spp. 70.95% produced Enterobacteriaceae spp. and 18.8% produced Pseudomonas 18.8%. Conclusion: Based on the results, the frequncy of b–lactamase Enzyme existence in isolated bacteria of nosocomial infection was very high, which can be due to the increase of resistance of b–lactam antibiotics in PATHOGEN BACTERIA.

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APA: Copy

JALALPOUR, SH., KASRA KERMANSHAHI, R., NOUHI, ASHRAF ALSADAT, ZARKESH ESFAHANI, S.H., & ABOUSAEIDI, H.. (2009). COMPARING THE FREQUENCY OF β-LACTAMASE ENZYME EXISTENCE IN ISOLATED NOSOCOMIAL INFECTION BACTERIA. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 8(3 (32)), 203-214. SID. https://sid.ir/paper/70843/en

Vancouver: Copy

JALALPOUR SH., KASRA KERMANSHAHI R., NOUHI ASHRAF ALSADAT, ZARKESH ESFAHANI S.H., ABOUSAEIDI H.. COMPARING THE FREQUENCY OF β-LACTAMASE ENZYME EXISTENCE IN ISOLATED NOSOCOMIAL INFECTION BACTERIA. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2009;8(3 (32)):203-214. Available from: https://sid.ir/paper/70843/en

IEEE: Copy

SH. JALALPOUR, R. KASRA KERMANSHAHI, ASHRAF ALSADAT NOUHI, S.H. ZARKESH ESFAHANI, and H. ABOUSAEIDI, “COMPARING THE FREQUENCY OF β-LACTAMASE ENZYME EXISTENCE IN ISOLATED NOSOCOMIAL INFECTION BACTERIA,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 8, no. 3 (32), pp. 203–214, 2009, [Online]. Available: https://sid.ir/paper/70843/en

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