THE EFFECTS OF ERRΑ (ESTROGEN-RELATED RECEPTOR ALPHA) INHIBITION ON THE SERUM LEVELS OF CHEMERIN, NESFATIN-1, AND APELIN AFTER ENDURANCE TRAINING IN MALE WISTAR RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JOUKAR S.; MAREFATI H.; AMINIZADEH S.; MASOUMI ARDAKANI Y.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Rafsanjan University of Medical Sciences Year:2018 | Volume:16 | Issue:10 Page(s): 901-912

Download Full-Text

Persian Verion

View:

638

Download:

Cites:

Information Journal Paper

Title

THE EFFECTS OF ERRΑ (ESTROGEN-RELATED RECEPTOR ALPHA) INHIBITION ON THE SERUM LEVELS OF CHEMERIN, NESFATIN-1, AND APELIN AFTER ENDURANCE TRAINING IN MALE WISTAR RATS

Author(s)

JOUKAR S. | MAREFATI H. | AMINIZADEH S. | MASOUMI ARDAKANI Y. | Issue Writer Certificate

Keywords

CHEMERINQ1

NESFATIN-1Q1

APELINQ1

ERR αQ1

ENDURANCE TRAININGQ1

RATQ2

Abstract

Background and Objectives: Adipokines as lipid-secreted proteins play an important role in controlling the metabolism of the body. The aim of the present study was to investigate the effects of ERRa (Estrogen-related receptor alpha) inhibition on the serum levels of CHEMERIN, NESFATIN-1, and APELIN after 4 weeks of ENDURANCE TRAINING in male Wistar RATs.Materials and Methods: In this experimental study, 32 adult male Wistar RATs were used. The animals were randomly divided into four equal groups including the control, control+XCT790, ENDURANCE TRAINING, and ENDURANCE TRAINING+XCT790. XCT790, as an ERRa inhibitor, was intraperitoneally injected at a dose of 0.48 mg /kg of body weight. The training groups performed running ENDURANCE TRAINING for four weeks (five sessions per week). At the start of the training, the speed was 15 meters per minute and the time was 20 minutes, and gradually increased to 27 meters per minute for 50 minutes. The ELIZA technique was utilized for measuring the serum levels of APELIN, CHEMERIN, and NESFATIN-1. One-way analysis of variance followed by Tukey post hoc test was used for between groups comparisons.Results: Serum levels of APELIN (P=0.168) and CHEMERIN (P=0.397) in the ENDURANCE TRAINING group had no significant difference compared to the control group. Serum levels of NESFATIN-1 in the ENDURANCE TRAINING group showed a significant increase compared to the control group (P=0.001). Also, APELIN serum levels (P=0.033) in the control+XCT790 group significantly decreased compared to the control group, but the serum levels of NESFATIN-1 showed a significant increase (P=0.001), while there was no significant difference in the serum levels of CHEMERIN compared to the control group (P= 0.718).Conclusion: The results suggest that NESFATIN-1is a factor that can be changed by the ENDURANCE TRAINING, and it can probably play a compensatory role in energy homeostasis disorders, but CHEMERIN does not change with ERRa inhibition.

Cites

No record.

References

No record.

Cite

APA: Copy

JOUKAR, S., MAREFATI, H., AMINIZADEH, S., & MASOUMI ARDAKANI, Y.. (2018). THE EFFECTS OF ERR? (ESTROGEN-RELATED RECEPTOR ALPHA) INHIBITION ON THE SERUM LEVELS OF CHEMERIN, NESFATIN-1, AND APELIN AFTER ENDURANCE TRAINING IN MALE WISTAR RATS. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 16(10 ), 901-912. SID. https://sid.ir/paper/70993/en

Vancouver: Copy

JOUKAR S., MAREFATI H., AMINIZADEH S., MASOUMI ARDAKANI Y.. THE EFFECTS OF ERR? (ESTROGEN-RELATED RECEPTOR ALPHA) INHIBITION ON THE SERUM LEVELS OF CHEMERIN, NESFATIN-1, AND APELIN AFTER ENDURANCE TRAINING IN MALE WISTAR RATS. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2018;16(10 ):901-912. Available from: https://sid.ir/paper/70993/en

IEEE: Copy

S. JOUKAR, H. MAREFATI, S. AMINIZADEH, and Y. MASOUMI ARDAKANI, “THE EFFECTS OF ERR? (ESTROGEN-RELATED RECEPTOR ALPHA) INHIBITION ON THE SERUM LEVELS OF CHEMERIN, NESFATIN-1, AND APELIN AFTER ENDURANCE TRAINING IN MALE WISTAR RATS,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 16, no. 10 , pp. 901–912, 2018, [Online]. Available: https://sid.ir/paper/70993/en

Related Journal Papers