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1

Information Journal Paper

Title

Anti-apoptotic Effects of Interval and Continued Training and Crocin on the Muscle Tissue of the Rats with Type II Diabetes Induced by a High-fat Diet

Pages

  130-137

Abstract

 Introduction: Diabetes is a metabolic disease, which is directly correlated with increased physical disabilities and muscle tissue damage. The present study aimed to investigate the anti-apoptotic effects of interval and Continued Training and Crocin on diabetic rats. Methods: In this study, 49 adult rats aged eight weeks with Diabetes inducaed by a high-fat diet and venous injection of streptozotocin were randomly assigned to seven groups, including high-intensity Interval Training (HIIT), low-intensity Continued Training (LICT), HIIT with Crocin consumption, LICT with Crocin consumption, Crocin consumption, sham, and control. The animals in the HIIT and LICT groups ran on a treadmill three sessions per week for eight weeks at the intensity of 80-85% and 50-55% of the maximum speed, respectively. The animals in the Crocin consumption groups received 25 mg/kg of Crocin weekly for eight weeks. Results: HIIT and LICT could significantly increase Bcl-2 and decrease Bax and p53, as well as the ratio of Bax and Bcl-2 (P≤ 0. 05). In addition, Crocin consumption could significantly increase Bcl-2 and decrease Bax (P≤ 0. 05). Training with Crocin consumption had interactive effects on the increase of Bcl-2 and decrease of p53 and ratio of Bax to Bcl-2 (P≤ 0. 05). Conclusion: According to the results, continued and Interval Training along with the consumption of Crocin exerted interactive anti-apoptotic effects on the rats with Diabetes induced by a high-fat diet.

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    APA: Copy

    MORADI, ALI, HOSSEINI, SEYED ALI, & NIKBAKHT, MASOUD. (2019). Anti-apoptotic Effects of Interval and Continued Training and Crocin on the Muscle Tissue of the Rats with Type II Diabetes Induced by a High-fat Diet. JOURNAL OF NUTRITION, FASTING AND HEALTH, 7(3), 130-137. SID. https://sid.ir/paper/717897/en

    Vancouver: Copy

    MORADI ALI, HOSSEINI SEYED ALI, NIKBAKHT MASOUD. Anti-apoptotic Effects of Interval and Continued Training and Crocin on the Muscle Tissue of the Rats with Type II Diabetes Induced by a High-fat Diet. JOURNAL OF NUTRITION, FASTING AND HEALTH[Internet]. 2019;7(3):130-137. Available from: https://sid.ir/paper/717897/en

    IEEE: Copy

    ALI MORADI, SEYED ALI HOSSEINI, and MASOUD NIKBAKHT, “Anti-apoptotic Effects of Interval and Continued Training and Crocin on the Muscle Tissue of the Rats with Type II Diabetes Induced by a High-fat Diet,” JOURNAL OF NUTRITION, FASTING AND HEALTH, vol. 7, no. 3, pp. 130–137, 2019, [Online]. Available: https://sid.ir/paper/717897/en

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