Antibiotic Resistance Patterns and Prevalence of PER and VEB Resistance Genes among Clinical Isolates of ESBL-Producing Acinetobacter Baumannii

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Vahidi Emami Hasan; KHALILIAN MOHADDESEH; Yadollahi Movahhed Narges

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL LABORATORY JOURNAL Year:2018 | Volume:12 | Issue:1 Page(s): 21-26

Download Full-Text

View:

204

Download:

Cites:

Information Journal Paper

Title

Antibiotic Resistance Patterns and Prevalence of PER and VEB Resistance Genes among Clinical Isolates of ESBL-Producing Acinetobacter Baumannii

Author(s)

Vahidi Emami Hasan | KHALILIAN MOHADDESEH | Yadollahi Movahhed Narges | Issue Writer Certificate

Keywords

Acinetobacter baumannii

Drug resistance

PER

VEB

Abstract

Background and Objectives: Acinetobacter species are responsible for a wide range of clinical complications in hospitalized patients. Antimicrobial treatment of clinical strains of PER/Acinetobacter baumannii/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">Acinetobacter baumannii may be compromised due to multiple-PER/Drug resistance/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">Drug resistance to -lactams. Aim of this study was to determine antibiotic resistance patterns and frequency of PER and VEB genes in A. baumannii isolates from hospitalized patients. Methods: In this cross-sectional study, 100 clinical strains of A. baumannii were isolated from patients hospitalized in Qom (Iran) using specific culture media and biochemical tests. The disk diffusion method was PERformed to determine resistance to some antibiotics. Minimum inhibitory concentration (MIC) for cefepime and ceftazidime was evaluated. Identification of ESBL-producing strains and presence of the PER and VEB genes were determined by combined disk test and polymerase chain reaction, respectively. Results: The isolates were highly resistant against cefixime, ceftriaxone and cefepime. Lowest level of resistance was against polymyxin B. In addition, 70% of the isolates were multi-drug resistant. MIC<128 μ g/ml to ceftazidime and cefepime was observed in 84% and 91% of the strains, respectively. Moreover, 21% of the strains were ESBL-positive and frequency of the PER and VEB genes was 47% and 32%, respectively. Conclusion: Majority of A. baumannii isolates are highly resistant to the tested antibiotics. Due to presence of the PER and VEB genes in the isolated strains, there is the possibility of resistance spread to other bacteria. Therefore, it is recommended to modify the consumption pattern for antibiotics and pay more attention to standards of nosocomial infection control.

Cites

Prevalence of blaTEM and blaVEB Genes in Multidrug-Resistant Acinetobacter baumannii Strains Isolated from Burn Wound Infection in Isfahan, Iran

References

No record.

Cite

APA: Copy

Vahidi Emami, Hasan, KHALILIAN, MOHADDESEH, & Yadollahi Movahhed, Narges. (2018). Antibiotic Resistance Patterns and Prevalence of PER and VEB Resistance Genes among Clinical Isolates of ESBL-Producing Acinetobacter Baumannii. MEDICAL LABORATORY JOURNAL, 12(1), 21-26. SID. https://sid.ir/paper/718378/en

Vancouver: Copy

Vahidi Emami Hasan, KHALILIAN MOHADDESEH, Yadollahi Movahhed Narges. Antibiotic Resistance Patterns and Prevalence of PER and VEB Resistance Genes among Clinical Isolates of ESBL-Producing Acinetobacter Baumannii. MEDICAL LABORATORY JOURNAL[Internet]. 2018;12(1):21-26. Available from: https://sid.ir/paper/718378/en

IEEE: Copy

Hasan Vahidi Emami, MOHADDESEH KHALILIAN, and Narges Yadollahi Movahhed, “Antibiotic Resistance Patterns and Prevalence of PER and VEB Resistance Genes among Clinical Isolates of ESBL-Producing Acinetobacter Baumannii,” MEDICAL LABORATORY JOURNAL, vol. 12, no. 1, pp. 21–26, 2018, [Online]. Available: https://sid.ir/paper/718378/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops