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Information Journal Paper

Title

Follow-Up of Chronic Hepatitis B Carriers: A Cross-Sectional Descriptive-Analytical Study

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Abstract

 Background: Hepatitis B is a serious liver infection and one of the 5 leading causes of death around the world. Chronic Hepatitis B has a variant Natural History. Around one-third of patients with chronic hepatitismayeventually develop cirrhosis or hepatocellular carcinoma. The aim of this study was to follow-up Chronic Hepatitis B carriers. Methods: This cross-sectional descriptive-analytical study was doneon235 Chronic Hepatitis Bcarriers, whoreferred to an infectious disease and tropical medicine clinic, in Birjand, Iran. All Chronic Hepatitis B carriers, who had referred to the study settings from 2005 to 2013, were approached. Data were entered in the SPSS software (v. 21. 0) and analyzed via the Chi-square and the Fisher’ s exact tests at a significance level of less than 0. 5. Results: The majority of participants were male (132 cases, 56. 2%) and married (193 cases, 82. 1%) and were aged 33. 3 0. 7. The followup mean time was 5 years with a range of 3 to 9 years. During this follow-up period, 10 individuals (4%) experienced seroconversion from hepatitis B surface antigen (HBsAg) positivity to negativity, 35 (15%) developed active hepatitis, 8 (3. 5%) developed cirrhosis, and 2 (1%) developed liver cancer. The remaining 180 participants (76. 5%) had inactive hepatitis. Among participants, 45 (19%) were hepatitis B e antigen-positive, 24. 5% of whom experienced positivity to negativity seroconversion. Conclusions: Most Chronic Hepatitis B carriers are primarily asymptomatic. However, 15% developed serious liver disease over time. Therefore, careful lifelong follow-up assessments are needed for early diagnosis and prevention.

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    APA: Copy

    Darvishpoor Kakhki, Tahereh, Bigari, Bita, Azarkar, Ghodsiyeh, & ZIAEE, MASOOD. (2017). Follow-Up of Chronic Hepatitis B Carriers: A Cross-Sectional Descriptive-Analytical Study. MODERN CARE JOURNAL, 14(1), 0-0. SID. https://sid.ir/paper/718796/en

    Vancouver: Copy

    Darvishpoor Kakhki Tahereh, Bigari Bita, Azarkar Ghodsiyeh, ZIAEE MASOOD. Follow-Up of Chronic Hepatitis B Carriers: A Cross-Sectional Descriptive-Analytical Study. MODERN CARE JOURNAL[Internet]. 2017;14(1):0-0. Available from: https://sid.ir/paper/718796/en

    IEEE: Copy

    Tahereh Darvishpoor Kakhki, Bita Bigari, Ghodsiyeh Azarkar, and MASOOD ZIAEE, “Follow-Up of Chronic Hepatitis B Carriers: A Cross-Sectional Descriptive-Analytical Study,” MODERN CARE JOURNAL, vol. 14, no. 1, pp. 0–0, 2017, [Online]. Available: https://sid.ir/paper/718796/en

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