Comparison of Human Chorionic Gonadotropin Test and Amnisure Test for Diagnosis of Premature Rapture of Membrane

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BAROOTI ESMAT; Darvish Soodabeh; KARIMAN NOUROSSADAT; YAZDANPANAH GHASEM

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Journal: MEDICAL LABORATORY JOURNAL Year:2019 | Volume:13 | Issue:1 Page(s): 28-32

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Title

Comparison of Human Chorionic Gonadotropin Test and Amnisure Test for Diagnosis of Premature Rapture of Membrane

Author(s)

BAROOTI ESMAT | Darvish Soodabeh | KARIMAN NOUROSSADAT | YAZDANPANAH GHASEM | Issue Writer Certificate

Keywords

Chorionic Gonadotropin

Fetal Membranes

Premature Rupture

Abstract

Background and objectives: Accurate diagnosis of preterm rupture of membrane (PROM) is critical during pregnancy, and researchers are seeking ways to decrease the rate of false negative results in diagnostic tests. In the present study, we compare diagnostic properties of Amnisure test and human Chorionic Gonadotropin (hCG) test for diagnosis of PROM. Methods: The study was performed on singleton pregnant women (gestational age: 20 to 41 weeks) who were referred to the Taleghani Hospital in Tehran (Iran) between December 2016 and December 2017. The study included 44 PROM patients and 44 control pregnant women. Speculum examination for cervicovaginal fluid washing, hCG test and Amnisure test were performed for all of patients. Statistical analysis of data was performed in SPSS software package (Version 18, Chicago, IL, USA) using t-test, Chi-square test, and Mann-Whitney test. P-values less than 0. 05 were considered statistically significant. Results: The Amnisure test had better sensitivity and specificity compared with the β-hCG test (95. 5% and 97. 7% vs. 93. 2% and 95. 5%). The Amnisure test also had higher positive and negative predictive values than the β-hCG test (97. 7% and 95. 5% vs. 93. 3% and 94. 3%). Diagnostic accuracy of the Amnisure test was also higher than that of the β-hCG test (96. 6% vs. 94. 3%). Conclusion: According to the results, the two tests have almost equal diagnostic power for detection of PROM during pregnancy.

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APA: Copy

BAROOTI, ESMAT, Darvish, Soodabeh, KARIMAN, NOUROSSADAT, & YAZDANPANAH, GHASEM. (2019). Comparison of Human Chorionic Gonadotropin Test and Amnisure Test for Diagnosis of Premature Rapture of Membrane. MEDICAL LABORATORY JOURNAL, 13(1), 28-32. SID. https://sid.ir/paper/719884/en

Vancouver: Copy

BAROOTI ESMAT, Darvish Soodabeh, KARIMAN NOUROSSADAT, YAZDANPANAH GHASEM. Comparison of Human Chorionic Gonadotropin Test and Amnisure Test for Diagnosis of Premature Rapture of Membrane. MEDICAL LABORATORY JOURNAL[Internet]. 2019;13(1):28-32. Available from: https://sid.ir/paper/719884/en

IEEE: Copy

ESMAT BAROOTI, Soodabeh Darvish, NOUROSSADAT KARIMAN, and GHASEM YAZDANPANAH, “Comparison of Human Chorionic Gonadotropin Test and Amnisure Test for Diagnosis of Premature Rapture of Membrane,” MEDICAL LABORATORY JOURNAL, vol. 13, no. 1, pp. 28–32, 2019, [Online]. Available: https://sid.ir/paper/719884/en

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