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Cites:

1

Information Journal Paper

Title

Effects of 8 Weeks of Resistance Training and IGF-1 Injection on Biochemical Markers of Cancer and Colorectal Structures in Rats

Pages

  23-29

Abstract

 Background and Objectives: We studied effects of eight weeks of resistance training and IGF-1 injection on serum level of IGF-1, IGFBP-3 and IGF-1/IGFBP-3 ratio in Wistar rats. Methods: We randomly divided 28 male Wistar rats into four groups of salineinjected control (C), resistance training+saline injection (RS), resistance training+IGF-1 injection (RI) and IGF-1 injection (II). Resistance training protocol consisted of climbing a ladder (three days/week with 5 reps/3 sets) while carrying a weight suspended from the tail for eight weeks. IGF-1 and saline (1. 5 μ g/kg/day) were injected before and after Exercise sessions. Serum IGF-1, IGFBP-3 and IGF-1/IGFBP-3 ratio and morphology of Colorectal tissue were evaluated. Results: Serum IGF-1 level and IGF-1/IGFBP-3 ratio decreased in the RS group compared to the other groups (P< 0. 05). Rats in the RS group had higher IGFBP-3 level than those in the II and RI groups (P< 0. 05). IGF-1 injection had no effect on morphology of Colorectal tissue. Conclusion: The resistance training reduces IGF-1 and increases IGFBP-3 levels, which might represent a link between resistance training and lower risk of Colorectal cancer.

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    • Cite

    APA: Copy

    ASKARI, BABISAN, BIJEH, NAHID, & RASHID LAMIR, AMIR. (2017). Effects of 8 Weeks of Resistance Training and IGF-1 Injection on Biochemical Markers of Cancer and Colorectal Structures in Rats. MEDICAL LABORATORY JOURNAL, 11(6), 23-29. SID. https://sid.ir/paper/719896/en

    Vancouver: Copy

    ASKARI BABISAN, BIJEH NAHID, RASHID LAMIR AMIR. Effects of 8 Weeks of Resistance Training and IGF-1 Injection on Biochemical Markers of Cancer and Colorectal Structures in Rats. MEDICAL LABORATORY JOURNAL[Internet]. 2017;11(6):23-29. Available from: https://sid.ir/paper/719896/en

    IEEE: Copy

    BABISAN ASKARI, NAHID BIJEH, and AMIR RASHID LAMIR, “Effects of 8 Weeks of Resistance Training and IGF-1 Injection on Biochemical Markers of Cancer and Colorectal Structures in Rats,” MEDICAL LABORATORY JOURNAL, vol. 11, no. 6, pp. 23–29, 2017, [Online]. Available: https://sid.ir/paper/719896/en

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