DETERMINING FACTORS AFFECTING TIME TO SPUTUM SMEAR CONVERSION IN PULMONARY TUBERCULOSIS PATIENTS USING COX SEMI-PARAMETRIC METHOD

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ARAB BORZOU ZAHRA; ESMAILY HABIBOLLAH; AFZAL AGHAEE MONAVAR; Samiei Amin; BAHRAMPOUR ABBAS

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Journal: Journal of Kerman University of Medical Sciences Year:2016 | Volume:23 | Issue:6 Page(s): 671-682

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Title

DETERMINING FACTORS AFFECTING TIME TO SPUTUM SMEAR CONVERSION IN PULMONARY TUBERCULOSIS PATIENTS USING COX SEMI-PARAMETRIC METHOD

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Keywords

PULMONARY TUBERCULOSISQ3

COX MODELSQ2

SPUTUMQ3

Abstract

Background & Aims: Tuberculosis is one of the most important diseases of century that involves all the human organs including lungs. Due to the yearly occurrence of 9 millions new cases and 1.5 millions deaths in the world, tuberculosis is in the center of attention. The aim of this study was to indentify factors affecting the time required for SPUTUM smear conversion in patients.Methods: This historical cohort study was performed on tuberculosis patients with pulmonary involvement and positive smear referred to Health Centers of Mashhad University of Medical Sciences from September 2012 to July 2014. The demographic characteristic of patients and features of disease were used as variables. Log Rank test, Kaplan-Meier method and Cox regression were used to analyze data (a<0.05).Results: Out of 1141 patients, 54.8% were female and 45.2% were male. The medium time to SPUTUM smear conversion was 2 months. At the end of the second and third months of treatment, respectively 78% and 89% of patients had negative smear. Based on Cox regression, gender and bacillus level at the beginning of treatment significantly affected the time to SPUTUM smear conversion.Conclusion: Special attention must be paid to the patient education and to the male patients and those with high level of bacillus at diagnosis time.

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APA: Copy

ARAB BORZOU, ZAHRA, ESMAILY, HABIBOLLAH, AFZAL AGHAEE, MONAVAR, Samiei, Amin, & BAHRAMPOUR, ABBAS. (2016). DETERMINING FACTORS AFFECTING TIME TO SPUTUM SMEAR CONVERSION IN PULMONARY TUBERCULOSIS PATIENTS USING COX SEMI-PARAMETRIC METHOD. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 23(6), 671-682. SID. https://sid.ir/paper/72/en

Vancouver: Copy

ARAB BORZOU ZAHRA, ESMAILY HABIBOLLAH, AFZAL AGHAEE MONAVAR, Samiei Amin, BAHRAMPOUR ABBAS. DETERMINING FACTORS AFFECTING TIME TO SPUTUM SMEAR CONVERSION IN PULMONARY TUBERCULOSIS PATIENTS USING COX SEMI-PARAMETRIC METHOD. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;23(6):671-682. Available from: https://sid.ir/paper/72/en

IEEE: Copy

ZAHRA ARAB BORZOU, HABIBOLLAH ESMAILY, MONAVAR AFZAL AGHAEE, Amin Samiei, and ABBAS BAHRAMPOUR, “DETERMINING FACTORS AFFECTING TIME TO SPUTUM SMEAR CONVERSION IN PULMONARY TUBERCULOSIS PATIENTS USING COX SEMI-PARAMETRIC METHOD,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 23, no. 6, pp. 671–682, 2016, [Online]. Available: https://sid.ir/paper/72/en

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