مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

215
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

134
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Histopathological study of erythropoietin protective effect on carbon monoxide-induced cardiotoxicity in rat

Pages

  1189-1193

Abstract

 Objective(s): Cardiotoxicity is one of the major consequences in carbon monoxide poisoning. Following our previous work, in this study we aimed to define the myocardium changes induced by carbon monoxide (CO) intoxication and evaluate erythropoietin (EPO) effect on CO Cardiotoxicity in Rat. Materials and Methods: Severe carbon monoxide toxicity induced by 3000 ppm CO in Wistar Rat. EPO was administRated (5000 IU/Kg, intraperitoneal injection) at the end of CO exposure and then the animals were re-oxygenated with the ambient air. Subsequently heart was removed and assessed by histopathology and electron microscopy examinations. Results: 3000 ppm CO induced significant myocardium injury; multiple foci of necrosis and lymphocyte infiltRation compare with the control (P˂ 0. 05). Electron microscopy examination showed myofibril lysis and mitochondrial swelling in myocardium due to 3000 ppm CO poisoning. However EPO administRation after CO exposure resulted in significant reduction in cardiomyocytes injury (P˂ 0. 05). Conclusion: Our results represented protective effect of EPO on cardiac injury induced by CO intoxication in Rat.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    ASGHARIAN REZAEE, MITRA, MOALLEM, SEYED ADEL, MOHAMMADPOUR, AMIR HOOSHANG, MAHMOUDI, MAHMOUD, SANKIAN, MOJTABA, FARZADNIA, MEHDI, ALAVI, HASSAN, & IMENSHAHIDI, MOHSEN. (2017). Histopathological study of erythropoietin protective effect on carbon monoxide-induced cardiotoxicity in rat. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 20(11), 1189-1193. SID. https://sid.ir/paper/722657/en

    Vancouver: Copy

    ASGHARIAN REZAEE MITRA, MOALLEM SEYED ADEL, MOHAMMADPOUR AMIR HOOSHANG, MAHMOUDI MAHMOUD, SANKIAN MOJTABA, FARZADNIA MEHDI, ALAVI HASSAN, IMENSHAHIDI MOHSEN. Histopathological study of erythropoietin protective effect on carbon monoxide-induced cardiotoxicity in rat. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2017;20(11):1189-1193. Available from: https://sid.ir/paper/722657/en

    IEEE: Copy

    MITRA ASGHARIAN REZAEE, SEYED ADEL MOALLEM, AMIR HOOSHANG MOHAMMADPOUR, MAHMOUD MAHMOUDI, MOJTABA SANKIAN, MEHDI FARZADNIA, HASSAN ALAVI, and MOHSEN IMENSHAHIDI, “Histopathological study of erythropoietin protective effect on carbon monoxide-induced cardiotoxicity in rat,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 20, no. 11, pp. 1189–1193, 2017, [Online]. Available: https://sid.ir/paper/722657/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button