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Information Journal Paper

Title

The effect of gamma radiation on plasma levels of zinc and selenium in nuclear medicine staff

Pages

  51-56

Keywords

Abstract

 Background and aims: Gamma radiation is widely being used in medical-imaging centers. The aim of this study was to measure possible alterations in Serum Zinc and Selenium levels among nuclear medicine staff. Methods: This cross-sectional study was carried out on 30 nuclear medicine staff as well as on 10 individuals as the control group. Blood samples (20 mL) were obtained from the participants and the Serum specimens were isolated by centrifugation at 4000 rpm for 7 minutes. The samples were then used for measurement of Zinc and Selenium levels. Zinc and Selenium levels were measured using atomic absorption spectroscopy (AAS) with a graphite furnace. The mean Serum levels of Zinc and Selenium were compared using SPSS. Results: The mean level of Zinc in the radiated group (70. 91± 14. 46 μ mol/L) was significantly lower than that in the control group (89. 75± 17. 35 μ mol/L) (P = 0. 002). A negative significant correlation was found between the duration of exposure to radiation and Zinc levels (P = 0. 005). Furthermore, a negative significant relationship was observed between the mean radiation dose after 5 years and Zinc concentration (P = 0. 019). Non-significant difference was found in the mean level of Selenium between control (1. 71± 0. 35 μ mol/L) and radiation (2. 13± 1. 12 μ mol/L) groups. Furthermore, no significant correlation was found between Selenium level and exposure time. Conclusion: Based on the results, declined level of Zinc can be considered as one of the possible mechanisms caused by Gamma radiation on cells which may be associated with oxidative damage. Therefore, Zinc therapy can be helpful for those who work at medical radiation centers; however, it merits further studies.

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    APA: Copy

    MIRNAMNIHA, MAHDIYEH, & Salehi Barough, Mehdi. (2019). The effect of gamma radiation on plasma levels of zinc and selenium in nuclear medicine staff. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 21(1), 51-56. SID. https://sid.ir/paper/729398/en

    Vancouver: Copy

    MIRNAMNIHA MAHDIYEH, Salehi Barough Mehdi. The effect of gamma radiation on plasma levels of zinc and selenium in nuclear medicine staff. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;21(1):51-56. Available from: https://sid.ir/paper/729398/en

    IEEE: Copy

    MAHDIYEH MIRNAMNIHA, and Mehdi Salehi Barough, “The effect of gamma radiation on plasma levels of zinc and selenium in nuclear medicine staff,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 1, pp. 51–56, 2019, [Online]. Available: https://sid.ir/paper/729398/en

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