SUBMUCOSAL AND MUSCULAR LAYERS FOR GANGLION CELLS IN DIAGNOSIS OF HIRSCHSPRUNGS DISEASE (H.D); A COMPARATIVE STUDY

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SHAFIGH E.; SIADATI S.; MOHAMMAD BAGHERZADEH TORBATI TH.; REZAEIAN R.; HAJIAN K.

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Journal: Journal of Babol University of Medical Sciences Year:2004 | Volume:6 | Issue:3 (23) Page(s): 26-31

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Title

SUBMUCOSAL AND MUSCULAR LAYERS FOR GANGLION CELLS IN DIAGNOSIS OF HIRSCHSPRUNGS DISEASE (H.D); A COMPARATIVE STUDY

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Keywords

HIRSCHSPRUNGS DISEASEQ3

FULL-THICKNESS BIOPSYQ4

GANGLION CELLQ4

RECTAL SUCTION BIOPSYQ4

Abstract

BACKGROUND AND OBJECTIVE: Hirsch sprung s disease (H.D) is the most common cause of lower gastrointestinal tract obstruction in newborns. Diagnosis of H.D was established by a full-thickness rectal biopsy, then it was replaced by RECTAL SUCTION BIOPSY, that is easier and has less complications. This study was done to compare the sub mucosa and muscular coat of rectal wall for GANGLION CELLs. METHODS: In this descriptive, analytical and cross-sectional study, data were obtained from 239 pathological reports in archive of Shahid Beheshti hospital, department of pathology from 1991 to 2001. Serial sections (up to 60 sections) were tested microscopically.FINDINGS: Sixty-one from 239 specimens were diagnosed as H.D (19.3%) and in 172 cases GANGLION CELLs were present in both muscular and sub mucosal layers (54.43%). Sensitivity of sub mucosa for presence of GANGLION CELLs was 96.6% and correlation between sub mucosal and muscular layers for absence of GANGLION CELL was 100% (p<0.05). CONCLUSION: The results showed a good correlation between advantages of serial sections of muscular and sub mucosal layers for presence of GANGLION CELLs. Probability of coincident presence of GANGLION CELLs in both layers was confirmed.

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ارزش تشخیصی باریم انما در بیماری هیرشپرونگ

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APA: Copy

SHAFIGH, E., SIADATI, S., MOHAMMAD BAGHERZADEH TORBATI, TH., REZAEIAN, R., & HAJIAN, K.. (2004). SUBMUCOSAL AND MUSCULAR LAYERS FOR GANGLION CELLS IN DIAGNOSIS OF HIRSCHSPRUNGS DISEASE (H.D); A COMPARATIVE STUDY. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 6(3 (23)), 26-31. SID. https://sid.ir/paper/73116/en

Vancouver: Copy

SHAFIGH E., SIADATI S., MOHAMMAD BAGHERZADEH TORBATI TH., REZAEIAN R., HAJIAN K.. SUBMUCOSAL AND MUSCULAR LAYERS FOR GANGLION CELLS IN DIAGNOSIS OF HIRSCHSPRUNGS DISEASE (H.D); A COMPARATIVE STUDY. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2004;6(3 (23)):26-31. Available from: https://sid.ir/paper/73116/en

IEEE: Copy

E. SHAFIGH, S. SIADATI, TH. MOHAMMAD BAGHERZADEH TORBATI, R. REZAEIAN, and K. HAJIAN, “SUBMUCOSAL AND MUSCULAR LAYERS FOR GANGLION CELLS IN DIAGNOSIS OF HIRSCHSPRUNGS DISEASE (H.D); A COMPARATIVE STUDY,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 6, no. 3 (23), pp. 26–31, 2004, [Online]. Available: https://sid.ir/paper/73116/en

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