OUTBREAK OF CAGA AND ICEA IN H. PYLORI STRAINS ISOLATED FROM PATIENTS WITH GASTRO DUODENAL DISEASESIN BABOL CITY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHOKRI SHIRVANI J.; RAJABNIA R.; TOHIDI F.; ASMAR M.; TAHERI HASAN

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS) Year:2008 | Volume:10 | Issue:1 (42) Page(s): 46-53

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

859

Download:

Cites:

Information Journal Paper

Title

OUTBREAK OF CAGA AND ICEA IN H. PYLORI STRAINS ISOLATED FROM PATIENTS WITH GASTRO DUODENAL DISEASESIN BABOL CITY

Author(s)

Keywords

HELICOBACTER PYLORIQ3

CAGAQ3

ICEAQ3

GASTERODUODENALQ3

Abstract

BACKGROUND AND OBJECTIVE: HELICOBACTER PYLORI is one of the most common bacteria that afflicts world' human population. Virulence factor of HELICOBACTER PYLORI have been associated with clinical outcome of the infection including gastritis, gastric ulcer (GU), duodenal ulcer (DU) and gastric cancer. The aim of the present study was to determine the outbreak of CAGA and ICEA genotypes of H. pylori in patients with gastroduodenal diseases in Babol, North of Iran.METHODS: Fifty patients with dyspepsia underwent gastroscopy and antral biopsy for histologic study. CAGA, ICEA, ICEA1 and ICEA2 genotypes were determined by PCR.FINDINGS: Of 30(60%) HP positive strains, 80% were positive for CAGA gene. CAGA genotype was positive in 91.7% (11 of 12), 73.3% (11 of 15) and 66.7% (2 of 3) of patients with gastritis, DU and GU, respectively. ICEA was positive in 21(70%) of all patients and ICEAl was found in 14(66.7%) isolates and ICEA2 was found in 23.8% isolates. ICEA1 and ICEA2 were not found in 2(9.5%). ICEA1 outbreak in patients with gastritis, DU and GU was 88.9%, 45.5% and 50%, respectively.CONCLUSION: Positive CAGA strain was more than negative CAGA and, ICEA1 was predominant strains in our patients with HP infection. We found that two genes other than ICEAl and ICEA2 in this study. It seems that new allele other than ICEA1 and ICEA2 genes are present in H. pylori.

Cites

No record.

References

A STUDY OF CAGA GENE IN HELICOBACTER PYLORI STRAINS ISOLATED FROM PATIENTS WITH NUD, PEPTIC ULCER AND GASTRIC CANCER BY PCR METHOD

Cite

APA: Copy

SHOKRI SHIRVANI, J., RAJABNIA, R., TOHIDI, F., ASMAR, M., & TAHERI, HASAN. (2008). OUTBREAK OF CAGA AND ICEA IN H. PYLORI STRAINS ISOLATED FROM PATIENTS WITH GASTRO DUODENAL DISEASESIN BABOL CITY. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 10(1 (42)), 46-53. SID. https://sid.ir/paper/73120/en

Vancouver: Copy

SHOKRI SHIRVANI J., RAJABNIA R., TOHIDI F., ASMAR M., TAHERI HASAN. OUTBREAK OF CAGA AND ICEA IN H. PYLORI STRAINS ISOLATED FROM PATIENTS WITH GASTRO DUODENAL DISEASESIN BABOL CITY. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2008;10(1 (42)):46-53. Available from: https://sid.ir/paper/73120/en

IEEE: Copy

J. SHOKRI SHIRVANI, R. RAJABNIA, F. TOHIDI, M. ASMAR, and HASAN TAHERI, “OUTBREAK OF CAGA AND ICEA IN H. PYLORI STRAINS ISOLATED FROM PATIENTS WITH GASTRO DUODENAL DISEASESIN BABOL CITY,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 10, no. 1 (42), pp. 46–53, 2008, [Online]. Available: https://sid.ir/paper/73120/en

Related Journal Papers