ROLE OF CENTRAL NORADRENERGIC SYSTEM ON FSH SECRETION INDUCED BY EXCITATORY AMINO ACIDS

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SHAHABI S.; MOGHADAMNIA ALI AKBAR

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Journal: JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS) Year:2001 | Volume:3 | Issue:1 (9) Page(s): 14-20

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Title

ROLE OF CENTRAL NORADRENERGIC SYSTEM ON FSH SECRETION INDUCED BY EXCITATORY AMINO ACIDS

Author(s)

SHAHABI S. | MOGHADAMNIA ALI AKBAR | Issue Writer Certificate

Keywords

CENTRAL NORADRENERGIC SYSTEMQ4

LOCUS COERULEUS NUCLEUSQ4

EXCITATORY AMINO ACIDQ4

FOLLICLE STIMULATING HORMONE (FSH)Q3

RATQ2

Abstract

OBJECTIVE: EXCITATORY AMINO ACIDs (EAA) and noradrenaline are known as a neurotransmitter which stimulates gonadotropin secretion in female and male animals. This study was designed to evaluate the involvement of CENTRAL NORADRENERGIC SYSTEM on FSH secretion induced by EAA in adult RATs. METHODS: RATs were implanted with monolateral cannula through the LC -SC (Locus Coeruleus –Sub coeruleus) by stereotaxy. Then saline or glutamate (2mg/ml) was injected into the cannula. Blood samples were drawn just 10 min. After injection and were prepared for IRMA (Immunoradiometric Assay). For investigating the involvement of LC -SC in nor adrenergic system, DSP-4 was used as an injection bilaterally one week before glutamate. FINDINGS: Microinjection of glutamate significantly increased the plasma level of FSH in comparison to saline in control group. Pretreatment with DSP-4 significantly decreased the plasma level of FSH before glutamate injection. CONCLUSION: The results indicate that LC-SC in adult RATs is one of the major sites affected by EAAs on FSH secretion by noradrenergic neurons.

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APA: Copy

SHAHABI, S., & MOGHADAMNIA, ALI AKBAR. (2001). ROLE OF CENTRAL NORADRENERGIC SYSTEM ON FSH SECRETION INDUCED BY EXCITATORY AMINO ACIDS. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 3(1 (9)), 14-20. SID. https://sid.ir/paper/73265/en

Vancouver: Copy

SHAHABI S., MOGHADAMNIA ALI AKBAR. ROLE OF CENTRAL NORADRENERGIC SYSTEM ON FSH SECRETION INDUCED BY EXCITATORY AMINO ACIDS. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2001;3(1 (9)):14-20. Available from: https://sid.ir/paper/73265/en

IEEE: Copy

S. SHAHABI, and ALI AKBAR MOGHADAMNIA, “ROLE OF CENTRAL NORADRENERGIC SYSTEM ON FSH SECRETION INDUCED BY EXCITATORY AMINO ACIDS,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 3, no. 1 (9), pp. 14–20, 2001, [Online]. Available: https://sid.ir/paper/73265/en

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