LOCAL APPLICATION OF AMITRIPTYLINE IN COMPLETION OF LOCAL ANESTHESIA IN IRREVERSMLE PULPITIS PAIN

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MOGHADAMNIA ALI AKBAR; PARTOVI MANDANA; MOHAMMADIANFAR I.; HAMIDI MAHMOUD REZA; BARADARAN M.; ZABIHI E.

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Journal: Journal of Babol University of Medical Sciences Year:2007 | Volume:8 | Issue:7 (35) Page(s): 24-29

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Title

LOCAL APPLICATION OF AMITRIPTYLINE IN COMPLETION OF LOCAL ANESTHESIA IN IRREVERSMLE PULPITIS PAIN

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Keywords

AMITRIPTYLINEQ3

TCASQ3

LOCAL ANESTHESIAQ3

ENDODENTICSQ3

IRREVERSIBLE PULPITISQ3

Abstract

BACKGROUND AND OBJECTIVES: AMITRIPTYLINE, a tricyclic antidepressant agent and with binding sites of the Na+ channels can overlap with the local anesthetic receptors. To assess the additional analgesic efficacy of local administration of 2% AMITRIPTYLINE in IRREVERSIBLE PULPITIS pain.METHODS: A randomized, double-blind, placebo-controlled study of 56 consenting adult patient was done. Patients applied placebo and AMITRIPTYLINE 2% as maximum 0.2 ml injection in the pulp chamber after taking lidocaine LOCAL ANESTHESIA. Patients recorded overall pain using a 0-10 visual analogue scale during time of zero (before treatment), 1, 3, 5, 7 and 9 minutes of the study period.FINDINGS: Overall pain was significantly reduced by AMITRIPTYLINE, a reduction by 92.5% in 9 min compared to zero.This finding showed a significantly difference when compared to placebo (p<0.001). On the other hand, the average pain intensity at zero and 9 min was significantly reduced by AMITRIPTYLINE (8.6 to 0.65, p<0.01).CONCLUSION: Local application of AMITRIPTYLINE 2% produces analgesia and can complete lidocaine LOCAL ANESTHESIA.According to the results, it could be considered as an adjutant therapy in control of pain due to IRREVERSIBLE PULPITIS.

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APA: Copy

MOGHADAMNIA, ALI AKBAR, PARTOVI, MANDANA, HAMIDI, MAHMOUD REZA, MOHAMMADIANFAR, I., BARADARAN, M., & ZABIHI, E.. (2007). LOCAL APPLICATION OF AMITRIPTYLINE IN COMPLETION OF LOCAL ANESTHESIA IN IRREVERSMLE PULPITIS PAIN. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 8(7 (35)), 24-29. SID. https://sid.ir/paper/73463/en

Vancouver: Copy

MOGHADAMNIA ALI AKBAR, PARTOVI MANDANA, HAMIDI MAHMOUD REZA, MOHAMMADIANFAR I., BARADARAN M., ZABIHI E.. LOCAL APPLICATION OF AMITRIPTYLINE IN COMPLETION OF LOCAL ANESTHESIA IN IRREVERSMLE PULPITIS PAIN. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2007;8(7 (35)):24-29. Available from: https://sid.ir/paper/73463/en

IEEE: Copy

ALI AKBAR MOGHADAMNIA, MANDANA PARTOVI, MAHMOUD REZA HAMIDI, I. MOHAMMADIANFAR, M. BARADARAN, and E. ZABIHI, “LOCAL APPLICATION OF AMITRIPTYLINE IN COMPLETION OF LOCAL ANESTHESIA IN IRREVERSMLE PULPITIS PAIN,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 8, no. 7 (35), pp. 24–29, 2007, [Online]. Available: https://sid.ir/paper/73463/en

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