The Analgesic Efficacy of Low Dose Dexamethasone Added to Bupivacaine in Ilioinguinal and Iliohypogastric Nerves Block in Patients Undergoing Inguinal Hernia Surgery Under Spinal Anesthesia

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KAYALHA HAMID; AHMADI GOORAJI SOMAYEH; PARSA HOSSEIN; Khezri Marzieh Beigom

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Journal Paper

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Journal: Journal of Advances in Medical and Biomedical Research Year:2019 | Volume:27 | Issue:124 Page(s): 16-22

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Title

The Analgesic Efficacy of Low Dose Dexamethasone Added to Bupivacaine in Ilioinguinal and Iliohypogastric Nerves Block in Patients Undergoing Inguinal Hernia Surgery Under Spinal Anesthesia

Author(s)

KAYALHA HAMID | AHMADI GOORAJI SOMAYEH | PARSA HOSSEIN | Khezri Marzieh Beigom | Issue Writer Certificate

Keywords

Dexamethasone

Inguinal herrniorraphy

Ilioinguinal nerve

Iliohypogastric nerve

Pain

Abstract

Background & Objective: Dexamethasone has been emerged as an adjuvant to local anesthetics to provide optimal analgesia. We have evaluated the postoperative analgesic efficacy of adding a low dose Dexamethasone to bupivacaine in ilioinguinal (II) and iliohypogastric (IH) blocks in patients undergoing inguinal herniorraphy under spinal anesthesia. Materials & Methods: 50 patients in the range of 20-80 years of age who had underwent elective surgery for the purpose of inguinal hernia repair under spinal anesthesia were recruited in a prospective, double-blinded, and randomized manner. At the end of the surgery, the patients received an II and IH block through the direct injection of drugs around nerves. Meanwhile, the control group received bupivacaine 0. 5% (2 cc) plus normal saline 1 cc (group C), and the Dexamethasone group received bupivacaine 0. 5% (2 cc) plus 4 mg (1 cc) Dexamethasone (group D). The Pain intensity was measured using the visual analogue scale (VAS) scale at 1, 2, 4, 12, and 24 hours after surgery. Results: The mean time of analgesic duration in group C (3. 6± 3. 8 hr) was greater than group D (1. 6± 1. 14 hr). This difference was statistically significant (P=0. 043). The Pain intensity 2 hours after surgery in group D was higher than in group C (median with IQR: 3± 4 vs. 2± 2; P=0. 007). The difference in the total analgesic consumption in group D (51. 1± 32. 4 mg) versus group C (26. 4± 33. 8 mg) was significant (P=0. 018). Conclusion: The addition of 4 mg Dexamethasone to bupivacaine in an II and IH block at the end of surgery in patients undergoing inguinal herniorraphy under spinal anesthesia failed to prolong the time to the first analgesic request. It provides only a minor analgesic effect 12 hours following the surgery.

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APA: Copy

KAYALHA, HAMID, AHMADI GOORAJI, SOMAYEH, PARSA, HOSSEIN, & Khezri, Marzieh Beigom. (2019). The Analgesic Efficacy of Low Dose Dexamethasone Added to Bupivacaine in Ilioinguinal and Iliohypogastric Nerves Block in Patients Undergoing Inguinal Hernia Surgery Under Spinal Anesthesia. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 27(124), 16-22. SID. https://sid.ir/paper/736422/en

Vancouver: Copy

KAYALHA HAMID, AHMADI GOORAJI SOMAYEH, PARSA HOSSEIN, Khezri Marzieh Beigom. The Analgesic Efficacy of Low Dose Dexamethasone Added to Bupivacaine in Ilioinguinal and Iliohypogastric Nerves Block in Patients Undergoing Inguinal Hernia Surgery Under Spinal Anesthesia. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2019;27(124):16-22. Available from: https://sid.ir/paper/736422/en

IEEE: Copy

HAMID KAYALHA, SOMAYEH AHMADI GOORAJI, HOSSEIN PARSA, and Marzieh Beigom Khezri, “The Analgesic Efficacy of Low Dose Dexamethasone Added to Bupivacaine in Ilioinguinal and Iliohypogastric Nerves Block in Patients Undergoing Inguinal Hernia Surgery Under Spinal Anesthesia,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 27, no. 124, pp. 16–22, 2019, [Online]. Available: https://sid.ir/paper/736422/en

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