Comparative Analysis of the Histopathologic Features, β-Catenin, and Ki67 Expression between Fibromatosis and Fibrosarcoma

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DEYHIMI PARVIZ; AREFIAN MAHMOUD REZA; MAHZOUNI PARVIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES) Year:2019 | Volume:20 | Issue:4 Page(s): 255-263

Download Full-Text

View:

134

Download:

Cites:

Information Journal Paper

Title

Comparative Analysis of the Histopathologic Features, β-Catenin, and Ki67 Expression between Fibromatosis and Fibrosarcoma

Author(s)

DEYHIMI PARVIZ | AREFIAN MAHMOUD REZA | MAHZOUNI PARVIN | Issue Writer Certificate

Keywords

Fibrosarcoma

Fibromatosis

Histopathology

-catenin

Ki-67

Abstract

Statement of the Problem: The biologic behavior and histopathological features of Fibromatosis are intermediate between those of fibroma and Fibrosarcoma. Purpose: The aim of the present study was to determine useful histopathologic and immunohistochemical characteristics for the differentiation of these lesions. Materials and Method: In this cross-sectional descriptive study, 40 specimens comprising 20 Fibrosarcoma and 20 Fibromatosis biopsies were selected. The histopathologic characteristics of these lesions were identified and immunohistochemical staining for Ki67 and β;-catenin markers was performed. Sections were examined by light microscopy and positively stained cells were counted. Results were analyzed by SPSS 20 using Chi-square test, Mannwhitney test, and t-test (p< 0. 05). Results: Statistical significant differences were observed between Fibromatosis and Fibrosarcoma in terms of distribution frequency, mitotic rate, herringbone pattern, cellularity, overlapping of nuclei, mean Ki67 score, and atypia rate. The other features including age, gender, necrosis, clarity of nucleoli and mean β;-catenin were not significantly different. Conclusion: The present findings suggest the mitotic figures, Ki67, herringbone pattern, cellularity, and atypia are useful to differentiate Fibromatosis from Fibrosarcoma.

Cites

No record.

References

No record.

Cite

APA: Copy

DEYHIMI, PARVIZ, AREFIAN, MAHMOUD REZA, & MAHZOUNI, PARVIN. (2019). Comparative Analysis of the Histopathologic Features, β-Catenin, and Ki67 Expression between Fibromatosis and Fibrosarcoma. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), 20(4), 255-263. SID. https://sid.ir/paper/740496/en

Vancouver: Copy

DEYHIMI PARVIZ, AREFIAN MAHMOUD REZA, MAHZOUNI PARVIN. Comparative Analysis of the Histopathologic Features, β-Catenin, and Ki67 Expression between Fibromatosis and Fibrosarcoma. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2019;20(4):255-263. Available from: https://sid.ir/paper/740496/en

IEEE: Copy

PARVIZ DEYHIMI, MAHMOUD REZA AREFIAN, and PARVIN MAHZOUNI, “Comparative Analysis of the Histopathologic Features, β-Catenin, and Ki67 Expression between Fibromatosis and Fibrosarcoma,” JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), vol. 20, no. 4, pp. 255–263, 2019, [Online]. Available: https://sid.ir/paper/740496/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops