A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs

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Tekade Avinash Ramrao; Yadav Jyoti Narayan

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Advanced Pharmaceutical Bulletin Year:2020 | Volume:10 | Issue:3 Page(s): 359-369

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Information Journal Paper

Title

A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs

Author(s)

Tekade Avinash Ramrao | Yadav Jyoti Narayan | Issue Writer Certificate

Keywords

Hydrophilic carriers

Mucilage’s

Natural gums

Solid dispersions

Solubility

Solubility enhancement

Abstract

A large number of hydrophilic and hydrophobic carriers in pharmaceutical excipients are available today which are used for formulation of Solid dispersions. Depending on nature of carriers the immediate release Solid dispersions and/or controlled release Solid dispersions can be formulated. Initially crystalline carriers were used which are transformed into amorphous Solid dispersions with enhanced properties. The carriers used previously were mostly synthetic one. Recent trend towards the use of natural carriers have replaced the use of synthetic carriers. This review is the overview of various synthetic, natural, semisynthetic, modified natural Hydrophilic carriers used for formulation of Solid dispersions.

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APA: Copy

Tekade, Avinash Ramrao, & Yadav, Jyoti Narayan. (2020). A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs. ADVANCED PHARMACEUTICAL BULLETIN, 10(3), 359-369. SID. https://sid.ir/paper/741491/en

Vancouver: Copy

Tekade Avinash Ramrao, Yadav Jyoti Narayan. A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2020;10(3):359-369. Available from: https://sid.ir/paper/741491/en

IEEE: Copy

Avinash Ramrao Tekade, and Jyoti Narayan Yadav, “A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 10, no. 3, pp. 359–369, 2020, [Online]. Available: https://sid.ir/paper/741491/en

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