EVALUATION OF MAST CELL AND BLOOD VESSEL DENSITY IN INFLAMMATORY PERIAPICAL LESIONS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SEIFI SAFOURA; SHAFAEI SHAHRIAR; BIZHANI ALI; ADHAMI FATEMEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Mashhad Dental School Year:2012 | Volume:36 | Issue:2 (81) Page(s): 121-132

Download Full-Text

Persian Verion

View:

807

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF MAST CELL AND BLOOD VESSEL DENSITY IN INFLAMMATORY PERIAPICAL LESIONS

Author(s)

SEIFI SAFOURA | SHAFAEI SHAHRIAR | BIZHANI ALI | ADHAMI FATEMEH | Issue Writer Certificate

Keywords

RADICULAR CYSTSQ2

PERIAPICAL GRANULOMASQ2

MAST CELLQ2

CD34Q2

TOLUIDINE BLUEQ2

Abstract

Introduction: RADICULAR CYSTSand PERIAPICAL GRANULOMAS are the most common periapical inflammatory lesions. However, the role of cellular immunity and microvesselsin their pathogenesis remains unknown. The aim of this study was to evaluate the MAST CELL density (MCD), mircovessel density (MVD) and investigating the correlation between their densities with each other in the above mentioned lesions.Materials & Methods: In this descriptive cross-sectional study, 40 paraffin blocks of mentioned lesions were selected from achieves of School of Dentistry, Babol University of Medical Sciences. Three sections were prepared from each block and stained by hematoxylin-eosin, TOLUIDINE BLUE, and immunohistochemically for CD34 to determine the score of inflammation, presence of MAST CELLs and degranulatedmast cells (DMCs), and MVD, respectively. The correlation between MCD and either inflammatory infiltrate or MVD was evaluated. Data analyzed by t student, Mann-Whitney and Spearman test.Results: MAST CELLs were present in all periapical inflammatory lesions; 15.4±14.8 for MCD, 7.2±6.1 for DMCs, and the ratio of DMCs to total number of MCs was 0.354±0.166 and 14.8+4.44 for blood vessel density in radicular cyst and 8.52±6.75, 2.91±2.1, 0.196±0.194 and 13±8.02 in PERIAPICAL GRANULOMAS, respectively. There was a positive correlation between MCD and MVD in radicular cyst (P=0.03, r=0.341), but not in PERIAPICAL GRANULOMAS (P=0.6, r=0.124). MCD and MVD increased with the score of inflammation in radicular cyst (P=0.001, r=0.7) and periapical granuloma (P=0.012, r=0.54).Conclusion: MAST CELLs and microvessels play a role in pathogenesis of periapical inflammatory lesions. In this study, the density of MAST CELLs and DMCs in radicular cyst was higher than PERIAPICAL GRANULOMAS, but no difference was observed regarding MVD in periapical inflammatory lesions. It seems that the relationship between MCD and MVD is different based on the clinical stage of periapical inflammatory lesions.

Cites

SURVEY OF MAST CELL DENSITY IN LARYNGEAL SQUAMOUS CELL CARCINOMA AND LARYNGEAL DYSPLASIA

References

No record.

Cite

APA: Copy

SEIFI, SAFOURA, SHAFAEI, SHAHRIAR, BIZHANI, ALI, & ADHAMI, FATEMEH. (2012). EVALUATION OF MAST CELL AND BLOOD VESSEL DENSITY IN INFLAMMATORY PERIAPICAL LESIONS. JOURNAL OF MASHHAD DENTAL SCHOOL, 36(2 (81)), 121-132. SID. https://sid.ir/paper/74167/en

Vancouver: Copy

SEIFI SAFOURA, SHAFAEI SHAHRIAR, BIZHANI ALI, ADHAMI FATEMEH. EVALUATION OF MAST CELL AND BLOOD VESSEL DENSITY IN INFLAMMATORY PERIAPICAL LESIONS. JOURNAL OF MASHHAD DENTAL SCHOOL[Internet]. 2012;36(2 (81)):121-132. Available from: https://sid.ir/paper/74167/en

IEEE: Copy

SAFOURA SEIFI, SHAHRIAR SHAFAEI, ALI BIZHANI, and FATEMEH ADHAMI, “EVALUATION OF MAST CELL AND BLOOD VESSEL DENSITY IN INFLAMMATORY PERIAPICAL LESIONS,” JOURNAL OF MASHHAD DENTAL SCHOOL, vol. 36, no. 2 (81), pp. 121–132, 2012, [Online]. Available: https://sid.ir/paper/74167/en

Related Journal Papers