Procalcitonin, C-Reactive Protein, and Neutrophil Ratio Contribute to the Diagnosis and Prognosis of Severe Acute Pancreatitis

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LIANG Yi; ZHAO Xianwei; MENG Fanliang

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Journal of Public Health Year:2019 | Volume:48 | Issue:12 Page(s): 2177-2186

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Title

Procalcitonin, C-Reactive Protein, and Neutrophil Ratio Contribute to the Diagnosis and Prognosis of Severe Acute Pancreatitis

Author(s)

LIANG Yi | ZHAO Xianwei | MENG Fanliang | Issue Writer Certificate

Keywords

Acute severe pancreatitis

Procalcitonin

C-reactive protein

Neutrophil ratio

Diagnosis

Abstract

Background: We aimed to explore the significance of Procalcitonin (PCT), C-reactive protein (CRP) and Neutrophil ratio (N%) in the early Diagnosis, treatment, and prognosis of severe acute pancreatitis (SAP). Methods: A total of 104 patients with SAP (SAP group) and 101 patients with mild acute pancreatitis (MAP) (MAP group) admitted to Affiliated Hospital of Jining Medical University, Jining, China were enrolled. The PCT and CRP in serum were detected by a full-automatic biochemical analyzer, and N% in peripheral blood was measured by a hemocyte analyzer. Results: The peripheral blood PCT, CRP, and N% in the SAP group were significantly higher than those in the MAP group (P<0. 001). Multivariate Logistic regression analysis showed that acute physiology and chronic health evaluation II (APACHE II) score, Ranson score, PCT, CRP, and N% were independent risk factors for SAP. The receiver operating characteristic (ROC) curve showed that the area under curve (AUC) of PCT, CRP, and N% in diagnosing SAP were 0. 906, 0. 840, and 0. 834 respectively, while that of combined detection was 0. 972. The AUC of PCT, CRP, and N% in diagnosing SAP death were 0. 907, 0. 900, and 0. 894, respectively. Conclusions: Peripheral blood PCT, CRP, and N% contribute to the Diagnosis and prognosis of SAP.

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APA: Copy

LIANG, Yi, ZHAO, Xianwei, & MENG, Fanliang. (2019). Procalcitonin, C-Reactive Protein, and Neutrophil Ratio Contribute to the Diagnosis and Prognosis of Severe Acute Pancreatitis. IRANIAN JOURNAL OF PUBLIC HEALTH, 48(12), 2177-2186. SID. https://sid.ir/paper/743161/en

Vancouver: Copy

LIANG Yi, ZHAO Xianwei, MENG Fanliang. Procalcitonin, C-Reactive Protein, and Neutrophil Ratio Contribute to the Diagnosis and Prognosis of Severe Acute Pancreatitis. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2019;48(12):2177-2186. Available from: https://sid.ir/paper/743161/en

IEEE: Copy

Yi LIANG, Xianwei ZHAO, and Fanliang MENG, “Procalcitonin, C-Reactive Protein, and Neutrophil Ratio Contribute to the Diagnosis and Prognosis of Severe Acute Pancreatitis,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 48, no. 12, pp. 2177–2186, 2019, [Online]. Available: https://sid.ir/paper/743161/en

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