مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Skeletal Muscle Hypertrophy, Insulin‑ like Growth Factor 1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of Whole‑ body Resistance Training

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  0-0

Abstract

 Background: sarcopenia describes the inevitable deterioration in muscle mass and strength that accompanies biological Aging. The purpose of this study was to investigate the effects of resistance training (RT) on quadriceps hypertrophy and related biochemistry in sarcopenic and healthy elderly men. Methods: A total of 31 elderly men (55– 70 years old) were classified as sarcopenic and nonsarcopenic and were divided into two groups. Both groups participated in a progressive RT program for 8 weeks. Results: Data indicated that the strength in the sarcopenic group increased more than the healthy group (P < 0. 05). Quadriceps cross‑ sectional area also increased more in the healthy group (P < 0. 05). myostatin concentration decreased in both groups after training (P < 0. 05). follistatin and testosterone increased in the healthy group; in contrast, only testosterone increased in the sarcopenic group after training (P < 0. 05). Conclusions: The findings from this study suggest that RT improves muscle cross‑ sectional area and biomarker‑ related muscle loss in both healthy and sarcopenic elderly men. The findings also demonstrate that growth factor profiles at baseline and changes in testosterone levels play an important role in muscle hypertrophy observed in both groups.

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    APA: Copy

    NEGARESH, RAOOF, Ranjbar, Rouholah, BAKER, JULIEN S., HABIBI, ABDOLHAMID, MOKHTARZADE, MOTAHARE, MOMEN GHARIBVAND, MOHAMMAD, & Fokin, Andrej. (2019). Skeletal Muscle Hypertrophy, Insulin‑ like Growth Factor 1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of Whole‑ body Resistance Training. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 10(-), 0-0. SID. https://sid.ir/paper/743210/en

    Vancouver: Copy

    NEGARESH RAOOF, Ranjbar Rouholah, BAKER JULIEN S., HABIBI ABDOLHAMID, MOKHTARZADE MOTAHARE, MOMEN GHARIBVAND MOHAMMAD, Fokin Andrej. Skeletal Muscle Hypertrophy, Insulin‑ like Growth Factor 1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of Whole‑ body Resistance Training. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE[Internet]. 2019;10(-):0-0. Available from: https://sid.ir/paper/743210/en

    IEEE: Copy

    RAOOF NEGARESH, Rouholah Ranjbar, JULIEN S. BAKER, ABDOLHAMID HABIBI, MOTAHARE MOKHTARZADE, MOHAMMAD MOMEN GHARIBVAND, and Andrej Fokin, “Skeletal Muscle Hypertrophy, Insulin‑ like Growth Factor 1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of Whole‑ body Resistance Training,” INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, vol. 10, no. -, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/743210/en

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