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Information Journal Paper

Title

Evaluation of Serum Vitamin D Level in Oral Lichen Planus Patients

Pages

  49-58

Abstract

 Introduction: Vitamin D is a secosteroid (pro)-hormone with multiple systematic effects, including the regulation of the immune system. Serum Vitamin D level affects the progression of some diseases, such as psoriasis and oral cancer. The study aimed to measure the serum Vitamin D level in patients with Oral Lichen Planus (OLP), which is an autoimmune and precancerous disease. Materials and Methods: This cross-sectional study was conducted on 66 patients with OLP and 30 healthy individuals. In addition, serum Vitamin D level was measured by ELISA method, and data analysis was performed using Mann– Whitney U and t-test. Results: In this research, 26 (39. 4%) patients with OLP had Vitamin D deficiency and 31 (47. 0%) subjects had an insufficient Vitamin D level. On the other hand, 9 (30. 0%) and 15 (50%) of the participants in the control group had Vitamin D deficiency and insufficient Vitamin D level, respectively. According to the results, no significant relationship was observed in the study groups regarding serum Vitamin D levels. However, a reverse and significant correlation was found between age and Vitamin D deficiency in the subjects (P=0. 015). Conclusion: According to the results of the study, low serum Vitamin D levels were observed in a high percentage of patients with OLP. Given the prevalence of Vitamin D deficiency in the society, extended research is required to evaluate the impact of this deficiency on pathogenesis of the disease.

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    APA: Copy

    Seif, Sepideh, JAFARI ASHKAVANDI, ZOHREH, MARDANI, MARYAM, & HAMIDIZADEH, NASRIN. (2018). Evaluation of Serum Vitamin D Level in Oral Lichen Planus Patients. JOURNAL OF MASHHAD DENTAL SCHOOL, 42(1 ), 49-58. SID. https://sid.ir/paper/74338/en

    Vancouver: Copy

    Seif Sepideh, JAFARI ASHKAVANDI ZOHREH, MARDANI MARYAM, HAMIDIZADEH NASRIN. Evaluation of Serum Vitamin D Level in Oral Lichen Planus Patients. JOURNAL OF MASHHAD DENTAL SCHOOL[Internet]. 2018;42(1 ):49-58. Available from: https://sid.ir/paper/74338/en

    IEEE: Copy

    Sepideh Seif, ZOHREH JAFARI ASHKAVANDI, MARYAM MARDANI, and NASRIN HAMIDIZADEH, “Evaluation of Serum Vitamin D Level in Oral Lichen Planus Patients,” JOURNAL OF MASHHAD DENTAL SCHOOL, vol. 42, no. 1 , pp. 49–58, 2018, [Online]. Available: https://sid.ir/paper/74338/en

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