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Information Journal Paper

Title

Prevalence of Hepatitis G Virus and Co-Infection with Hepatitis B Virus and Hepatitis C Virus Among Hemodialysis Patients in Ahvaz, Iran

Pages

  0-0

Abstract

 Background: Patients on hemodialysis are at a high-risk for acquiring blood-borne infections, such as hepatitis G, hepatitis C, and Hepatitis B Viruses. The aim of this investigation was to determine the Prevalence of HGV infection among patients on hemodialysis and its co-infection with hepatitis C and B viruses in Ahvaz. Methods: Blood samples were collected from patients on hemodialysis during January to July, 2016. RNAs were extracted from sera and cDNA was prepared using the kit. The nested-polymerase chain reaction (PCR) and sequencing of positive samples were carried out to determine hepatitis G virus genotypes. In addition, to evaluate the co-infection of HGV with hepatitis C and Hepatitis B Virus infections, the sera of all the individuals were tested for Hepatitis C Virus antibody and HBs-Ag by enzyme linked immunosorbent assay (ELISA) assay. Results: The HGV RNA was found in 10% of the patients with dominant genotype 2a. About 2% of the patients on hemodialysis were co-infected with Hepatitis C Virus while 1% of them was co-infected with Hepatitis B Virus. The statistical analysis revealed that there was a significant correlation (P < 0. 01) between duration of the hemodialysis process and hepatitis G virus infectivity. Conclusions: The present study showed that patients, who used the hemodialysis devices in this city, were infected with Hepatitis G, hepatitis B, and Hepatitis C Viruses. The data indicates that duration of dialysis is significantly related to infection of Hepatitis G virus. Therefore, it is critical to control the sterility of these equipment for intercepting cross-infectivity.

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    APA: Copy

    MAKVANDI, MANOOCHEHR, NISI, NILOOFAR, & Nahid Samiei, Rahil. (2018). Prevalence of Hepatitis G Virus and Co-Infection with Hepatitis B Virus and Hepatitis C Virus Among Hemodialysis Patients in Ahvaz, Iran. JUNDISHAPUR JOURNAL OF CHRONIC DISEASE CARE, 7(2), 0-0. SID. https://sid.ir/paper/744607/en

    Vancouver: Copy

    MAKVANDI MANOOCHEHR, NISI NILOOFAR, Nahid Samiei Rahil. Prevalence of Hepatitis G Virus and Co-Infection with Hepatitis B Virus and Hepatitis C Virus Among Hemodialysis Patients in Ahvaz, Iran. JUNDISHAPUR JOURNAL OF CHRONIC DISEASE CARE[Internet]. 2018;7(2):0-0. Available from: https://sid.ir/paper/744607/en

    IEEE: Copy

    MANOOCHEHR MAKVANDI, NILOOFAR NISI, and Rahil Nahid Samiei, “Prevalence of Hepatitis G Virus and Co-Infection with Hepatitis B Virus and Hepatitis C Virus Among Hemodialysis Patients in Ahvaz, Iran,” JUNDISHAPUR JOURNAL OF CHRONIC DISEASE CARE, vol. 7, no. 2, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/744607/en

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