Anti-tuberculosis and cytotoxic evaluation of the seaweed Sargassum boveanum

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AKBARI VAJIHE; Zafari Saeed; YEGDANEH AFSANEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: RESEARCH IN PHARMACEUTICAL SCIENCES (RPS) Year:2018 | Volume:13 | Issue:1 Page(s): 30-37

Download Full-Text

View:

149

Download:

Cites:

Information Journal Paper

Title

Anti-tuberculosis and cytotoxic evaluation of the seaweed Sargassum boveanum

Author(s)

AKBARI VAJIHE | Zafari Saeed | YEGDANEH AFSANEH | Issue Writer Certificate

Keywords

Sargassum

Persian Gulf

Tuberculosis

Cytotoxic

Abstract

Marine seaweeds produce a variety of compounds with different biological activities, including antiTuberculosis and anticancer effects. The aim of this study was to investigate anti-Tuberculosis activity of Sargassum boveanum (S. boveanum) and Cytotoxicity of different fractions of this seaweed. S. boveanum was collected from Persian Gulf. The plant was extracted by maceration with methanol-ethyl acetate solvent. The extract was evaporated and partitioned by Kupchan method to yield hexane, tricholoroethane, chloroform, and butanol partitions. The anti-Tuberculosis activity of the crude extract and toxicity of the fractions were investigated using green fluorescent protein reporter microplate assay and 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay methods, respectively. The cell survivals of HeLa cell were decreased by increasing the concentration of the extracts. The IC50 values of hexane, tricholoroethane, chloroform, and butanol partitions were 150. 3 ± 23. 10, 437. 0 ± 147. 3, 110. 4 ± 33. 67, and 1025. 0 ± 15. 20 μ g/mL, respectively. The crude extract was not active against Tuberculosis. This study reveals that different partitions of S. boveanum have Cytotoxic activity against the cancer cell lines.

Cites

Evaluation of the content and bioactivity of four macroalgae species from the Persian Gulf

References

No record.

Cite

APA: Copy

AKBARI, VAJIHE, Zafari, Saeed, & YEGDANEH, AFSANEH. (2018). Anti-tuberculosis and cytotoxic evaluation of the seaweed Sargassum boveanum. RESEARCH IN PHARMACEUTICAL SCIENCES (RPS), 13(1), 30-37. SID. https://sid.ir/paper/745356/en

Vancouver: Copy

AKBARI VAJIHE, Zafari Saeed, YEGDANEH AFSANEH. Anti-tuberculosis and cytotoxic evaluation of the seaweed Sargassum boveanum. RESEARCH IN PHARMACEUTICAL SCIENCES (RPS)[Internet]. 2018;13(1):30-37. Available from: https://sid.ir/paper/745356/en

IEEE: Copy

VAJIHE AKBARI, Saeed Zafari, and AFSANEH YEGDANEH, “Anti-tuberculosis and cytotoxic evaluation of the seaweed Sargassum boveanum,” RESEARCH IN PHARMACEUTICAL SCIENCES (RPS), vol. 13, no. 1, pp. 30–37, 2018, [Online]. Available: https://sid.ir/paper/745356/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops