Effect of Cucurbita Maxima on Control of Blood Glucose in Diabetic Critically Ill Patients

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MAHMOODPOOR ATA; Medghalchi Mahsa; NAZEMIYEH HOSSEIN; ASGHARIAN PARINA; SHADVAR KAMRAN; HAMISHEHKAR HADI

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Journal: Advanced Pharmaceutical Bulletin Year:2018 | Volume:8 | Issue:2 Page(s): 347-351

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Title

Effect of Cucurbita Maxima on Control of Blood Glucose in Diabetic Critically Ill Patients

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Keywords

Cucurbita maxima

Blood glucose

Hyperglycemia

Critical illness

Intensive care unit

Abstract

Purpose: Cucurbita maxima Duchense (C. maxima) has been widely used in China and Mexico as a hypoglycemic plant for controlling Blood glucose in diabetic patients. Furthermore, in northwest of Iran, this plant is used traditionally for controlling of diabetes. We examined the effect of C. maxima pulp besides insulin on control of Hyperglycemia in diabetic patients admitted to Intensive care unit (ICU). Methods: Twenty critically ill patients who were admitted to the ICU were enrolled in this study. 5g lyophilized powder of C. maxima was administrated every 12 hours for 3 days. Moreover, Blood glucose level and insulin dose were measured every 1-4 hours during 3 days before administration and 3days at the time of C. maxima administration. Results: The average of glucose level in 3 days before C. maxima administration was 214. 9 ± 55. 7 mg/dl, while in 3 days during C. maxima administration it was decreased to 178. 4 ± 36. 1 mg/dl (P<0. 001). Additionally, the average insulin dose during 3 days before intervention was 48. 05 ± 36. 5 IU and during the 3 days of C. maxima administration was decreased to 39. 5 ± 27. 8 IU (P=0. 06). Conclusion: It seems that C. maxima may decrease high Blood glucose level fast and effective in diabetic critically ill patients.

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APA: Copy

MAHMOODPOOR, ATA, Medghalchi, Mahsa, NAZEMIYEH, HOSSEIN, ASGHARIAN, PARINA, SHADVAR, KAMRAN, & HAMISHEHKAR, HADI. (2018). Effect of Cucurbita Maxima on Control of Blood Glucose in Diabetic Critically Ill Patients. ADVANCED PHARMACEUTICAL BULLETIN, 8(2), 347-351. SID. https://sid.ir/paper/745773/en

Vancouver: Copy

MAHMOODPOOR ATA, Medghalchi Mahsa, NAZEMIYEH HOSSEIN, ASGHARIAN PARINA, SHADVAR KAMRAN, HAMISHEHKAR HADI. Effect of Cucurbita Maxima on Control of Blood Glucose in Diabetic Critically Ill Patients. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2018;8(2):347-351. Available from: https://sid.ir/paper/745773/en

IEEE: Copy

ATA MAHMOODPOOR, Mahsa Medghalchi, HOSSEIN NAZEMIYEH, PARINA ASGHARIAN, KAMRAN SHADVAR, and HADI HAMISHEHKAR, “Effect of Cucurbita Maxima on Control of Blood Glucose in Diabetic Critically Ill Patients,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 8, no. 2, pp. 347–351, 2018, [Online]. Available: https://sid.ir/paper/745773/en

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