Design of novel Surfactant Modified Carbon Nanotube Paste Electrochemical Sensor for the Sensitive Investigation of Tyrosine as a Pharmaceutical Drug

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Hareesha Nagarajappa; Gowda Manjunatha Jamballi Gangadharappa; Raril Chenthattil; Tigari Girish

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Journal: Advanced Pharmaceutical Bulletin Year:2019 | Volume:9 | Issue:1 Page(s): 132-137

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Title

Design of novel Surfactant Modified Carbon Nanotube Paste Electrochemical Sensor for the Sensitive Investigation of Tyrosine as a Pharmaceutical Drug

Author(s)

Hareesha Nagarajappa | Gowda Manjunatha Jamballi Gangadharappa | Raril Chenthattil | Tigari Girish | Issue Writer Certificate

Keywords

Carbon nanotube

Sodium dodecyl sulfate

Tyrosine

Voltammetry

Abstract

Purpose: The novel Sodium dodecyl sulfate modified Carbon nanotube paste electrode (SDS/ CNTPE) was used as a sensitive sensor for the electrochemical investigation of L-Tyrosine (TY). Methods: The electrochemical analysis of TY was displayed through cyclic Voltammetry (CV) and differential pulse Voltammetry (DPV). The surface morphology of SDS/CNTPE and bare Carbon nanotube past electrode (BCNTPE) was reviewed trough field emission scanning electron microscopy (FESEM). Results: The functioning SDS/CNTPE shows a voltammetric response with superior sensitivity towards TY. This study was conducted using a phosphate buffer solution having neutral pH (pH=7. 0). The correlation between the oxidation peak current of TY and concentration of TY was achieved linearly in CV method, in the range 2. 0×10-6 to 5 ×10-5 M with the detection limit 729 nM and limit of quantification 2. 43 μ M. The investigated voltammetric study at SDS/CNTPE was also adopted in the examination of TY concentration in a pharmaceutical medicine as a real sample with the recovery of 97% to 98%. Conclusion: The modified electrode demonstrates optimum sensitivity, constancy, reproducibility, and repeatability during the electrocatalytic activity of TY.

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APA: Copy

Hareesha, Nagarajappa, Gowda Manjunatha, Jamballi Gangadharappa, Raril, Chenthattil, & Tigari, Girish. (2019). Design of novel Surfactant Modified Carbon Nanotube Paste Electrochemical Sensor for the Sensitive Investigation of Tyrosine as a Pharmaceutical Drug. ADVANCED PHARMACEUTICAL BULLETIN, 9(1), 132-137. SID. https://sid.ir/paper/745877/en

Vancouver: Copy

Hareesha Nagarajappa, Gowda Manjunatha Jamballi Gangadharappa, Raril Chenthattil, Tigari Girish. Design of novel Surfactant Modified Carbon Nanotube Paste Electrochemical Sensor for the Sensitive Investigation of Tyrosine as a Pharmaceutical Drug. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2019;9(1):132-137. Available from: https://sid.ir/paper/745877/en

IEEE: Copy

Nagarajappa Hareesha, Jamballi Gangadharappa Gowda Manjunatha, Chenthattil Raril, and Girish Tigari, “Design of novel Surfactant Modified Carbon Nanotube Paste Electrochemical Sensor for the Sensitive Investigation of Tyrosine as a Pharmaceutical Drug,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 9, no. 1, pp. 132–137, 2019, [Online]. Available: https://sid.ir/paper/745877/en

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