مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

122
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

74
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Effect of Predatory Stress Before Fertilization on Body Weight and Pentylenetetrazole-Induced Seizure in Rat Offspring

Pages

  97-104

Abstract

 Background & Objective: Spermatogenesis and oogenesis stress is a primary epigenetic element that can cause lifelong modifications in neural system functions. This study was designed to elucidate whether Preconceptional stress during spermatogenesis and oogenesis affects the seizure behaviors and Body weight of the offspring later in life. Materials & Methods: In this experimental study, 16 male and 32 female adult Rats were included. Half of the Rats were subjected to predatory stress. Then, they were coupled as follows: both subjects were intact as the control group (MC-FC), both subjects were stressed (MS-FS), male control/female stressed (MC-FS), and male stressed/female control (MS-FC). The pups were weighed and assessed for pentylenetetrazole-induced Seizures. In addition, aniline blue staining was performed to study the chromatin maturity of the sperm in male parents immediately after copulation. Results: The latency of the first seizure behavior significantly diminished in stressed pups, and the duration of focal and generalized Seizures significantly increased in the stressed Rats. In addition, the Body weight of the pups decreased in the stress groups compared to control Rats, and a significant decrease was detected in the chromatin maturity of sperms in stressed Rats. Conclusion: Stress during spermatogenesis and oogenesis can be critical for the general growth (Body weight) and seizure susceptibility of the offspring. Therefore, to improve reproductive outcomes, stress-lowering interventions are better to be started before conception.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    SABOORY, EHSAN, Mahmoodkhani, Maryam, ROSHAN MILANI, SHIVA, & RASMI, YOUSEF. (2020). Effect of Predatory Stress Before Fertilization on Body Weight and Pentylenetetrazole-Induced Seizure in Rat Offspring. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 28(127), 97-104. SID. https://sid.ir/paper/747144/en

    Vancouver: Copy

    SABOORY EHSAN, Mahmoodkhani Maryam, ROSHAN MILANI SHIVA, RASMI YOUSEF. Effect of Predatory Stress Before Fertilization on Body Weight and Pentylenetetrazole-Induced Seizure in Rat Offspring. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2020;28(127):97-104. Available from: https://sid.ir/paper/747144/en

    IEEE: Copy

    EHSAN SABOORY, Maryam Mahmoodkhani, SHIVA ROSHAN MILANI, and YOUSEF RASMI, “Effect of Predatory Stress Before Fertilization on Body Weight and Pentylenetetrazole-Induced Seizure in Rat Offspring,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 28, no. 127, pp. 97–104, 2020, [Online]. Available: https://sid.ir/paper/747144/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button