مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

119
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

88
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Vitamin B12 and Folate Status in Patients with Epilepsy Under Levetiracetam Monotherapy

Pages

  0-0

Abstract

 Background: Antiepileptic drugs (AEDs) may lead to an increase in the plasma concentration of homocysteine. There is limited information, especially from Iran, regarding the risk in patients who are treated with levetiracetam as a new type of AED. The aim of the present study was to investigate the effect of levetiracetam on plasma homocysteine, vitamin B12, and folate levels in adult patients with epilepsy. Methods: We conducted a case‑ control study and enrolled adult patients with epilepsy who had received monotherapy with levetiracetam for at least 6 months at some time prior to the study. homocysteine serum, vitamin B12, and folate were measured, and folate and vitamin B12 intake was determined by the food frequency questionnaire (FFQ). Results: Thirty‑ three patients on levetiracetam and 35 control subjects aged between 18 and 60 years were enrolled. No statistically significant differences in the means of the serum markers of vitamin B12, FA, and homocysteine levels were found between the two groups. In the first model, i. e., the crude model, no significant differences were observed in the serum concentrations of homocysteine, vitamin B12, and folate. In the second model, education was considered, and body mass index and folate intake was controlled with no significant difference being observed in the mean homocysteine serum level. Conclusions: Treatment with levetiracetam in patients with epilepsy has no effect on the serum levels concentrations of homocysteine, vitamin B12, and folate. This medication is suggested for patients who use AEDs on a long‑ term basis and at high dosages.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Mahdavi, Atena, ALAVI NAEINI, AMIRMANSOUR, NAJAFI, MOHAMMADREZA, Ghazvini, Mohammadreza, & MARACY, MOHAMMADREZA. (2019). Vitamin B12 and Folate Status in Patients with Epilepsy Under Levetiracetam Monotherapy. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 10(-), 0-0. SID. https://sid.ir/paper/750313/en

    Vancouver: Copy

    Mahdavi Atena, ALAVI NAEINI AMIRMANSOUR, NAJAFI MOHAMMADREZA, Ghazvini Mohammadreza, MARACY MOHAMMADREZA. Vitamin B12 and Folate Status in Patients with Epilepsy Under Levetiracetam Monotherapy. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE[Internet]. 2019;10(-):0-0. Available from: https://sid.ir/paper/750313/en

    IEEE: Copy

    Atena Mahdavi, AMIRMANSOUR ALAVI NAEINI, MOHAMMADREZA NAJAFI, Mohammadreza Ghazvini, and MOHAMMADREZA MARACY, “Vitamin B12 and Folate Status in Patients with Epilepsy Under Levetiracetam Monotherapy,” INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, vol. 10, no. -, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/750313/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button