Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine

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NAFAR MOHSEN; DALILI NOOSHIN; SAMAVAT SHIVA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Kidney Diseases Year:2020 | Volume:14 | Issue:5 Page(s): 335-347

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Information Journal Paper

Title

Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine

Author(s)

NAFAR MOHSEN | DALILI NOOSHIN | SAMAVAT SHIVA | Issue Writer Certificate

Keywords

membranous nephropathy

biomarkers

proteomics

transcriptomes

microRNA

extracellular vesicle

podocalyxin

PI3K/AKT

PLA2R

THSD7A

NELL-1

podocyte

Abstract

membranous nephropathy (MN) as one of the most common glomerulonephritis still relies on an invasive procedure of kidney biopsy for precise recognition. Over the recent past years noninvasive methods using wide range of biomarkers have been developed in order to diagnose and estimating the final prognosis of MN. Plasma, urine and tissue are readily accessible specimens for identification of these biomarkers. In order to utilize a single biomarker or a panel of them for detection of a specific entity, many factors should taking into consideration like the accuracy, precision, and validity, accompanying with being available and cost effective. This review is focused on recently developed biomarkers and their application on the diagnosis besides determining the prognosis of MN. The clinical utilities and limitations of each biomarker are discussed in details.

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APA: Copy

NAFAR, MOHSEN, DALILI, NOOSHIN, & SAMAVAT, SHIVA. (2020). Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 14(5), 335-347. SID. https://sid.ir/paper/751726/en

Vancouver: Copy

NAFAR MOHSEN, DALILI NOOSHIN, SAMAVAT SHIVA. Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)[Internet]. 2020;14(5):335-347. Available from: https://sid.ir/paper/751726/en

IEEE: Copy

MOHSEN NAFAR, NOOSHIN DALILI, and SHIVA SAMAVAT, “Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine,” IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), vol. 14, no. 5, pp. 335–347, 2020, [Online]. Available: https://sid.ir/paper/751726/en

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