Evaluation of radiochemical purities of routinely used radiopharmaceuticals: Three years’ experience of a single institute

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ULLAH HAMEED; AHMAD IFTIKHAR; Khattak Muhammad Rauf; Shah Shoab; Ahmad Shakil; Khan Kamran; Ahmad Syed Zeeshan

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF NUCLEAR MEDICINE Year:2019 | Volume:27 | Issue:1 (SERIAL NUMBER 52) Page(s): 19-25

Download Full-Text

View:

161

Download:

162

Cites:

Information Journal Paper

Title

Evaluation of radiochemical purities of routinely used radiopharmaceuticals: Three years’ experience of a single institute

Author(s)

Keywords

Radiochemical purity

Rf values

Chromatogram

Stationary phase

Radiopharmaceuticals

Abstract

Introduction: Radiochemical purity (RCP) is a routine quality control test carried out at nuclear medicine to determine the concentration of various chemical species present in the Radiopharmaceuticals (RPs). The present work describes three years of experience in a single institute for the measurement of these impurities in the RPs preparations. Methods: The RCP of different cold kit preparations were performed by chromatographic methods. Specifically, a small drop of the aliquot was spotted on the specific paper acting as the Stationary phase and then developed in different solvents as mobile phases. The developed Chromatograms were then quantified for various chemical species by Mini TLC scanner or well type counter. Results: The retention factor (Rf) values for the different chemical species in the labeling of RP were measured by using single, double or triple solvent systems. It was observed that 2. 70% of the kits had RCP less than the acceptable limit whereas 97. 30% kits were found within the permissible levels. Conclusion: Chromatographic techniques used for the assessment of RCP offer sufficiently good results for identification and separation of different chemical impurities.

Cites

No record.

References

No record.

Cite

APA: Copy

ULLAH, HAMEED, AHMAD, IFTIKHAR, Khattak, Muhammad Rauf, Shah, Shoab, Ahmad, Shakil, Khan, Kamran, & Ahmad, Syed Zeeshan. (2019). Evaluation of radiochemical purities of routinely used radiopharmaceuticals: Three years’ experience of a single institute. IRANIAN JOURNAL OF NUCLEAR MEDICINE, 27(1 (SERIAL NUMBER 52)), 19-25. SID. https://sid.ir/paper/751872/en

Vancouver: Copy

ULLAH HAMEED, AHMAD IFTIKHAR, Khattak Muhammad Rauf, Shah Shoab, Ahmad Shakil, Khan Kamran, Ahmad Syed Zeeshan. Evaluation of radiochemical purities of routinely used radiopharmaceuticals: Three years’ experience of a single institute. IRANIAN JOURNAL OF NUCLEAR MEDICINE[Internet]. 2019;27(1 (SERIAL NUMBER 52)):19-25. Available from: https://sid.ir/paper/751872/en

IEEE: Copy

HAMEED ULLAH, IFTIKHAR AHMAD, Muhammad Rauf Khattak, Shoab Shah, Shakil Ahmad, Kamran Khan, and Syed Zeeshan Ahmad, “Evaluation of radiochemical purities of routinely used radiopharmaceuticals: Three years’ experience of a single institute,” IRANIAN JOURNAL OF NUCLEAR MEDICINE, vol. 27, no. 1 (SERIAL NUMBER 52), pp. 19–25, 2019, [Online]. Available: https://sid.ir/paper/751872/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops