The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects

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AGHAMOHAMMADZADEH NASER; Dolatkhah Neda; HASHEMIAN MARYAM; SHAKOURI SEYED KAZEM; HASANPOUR SAEED

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Journal: Caspian Journal of Internal Medicine Year:2020 | Volume:11 | Issue:3 Page(s): 267-277

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Title

The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects

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Keywords

25-hydroxyvitamin D

Diabetes mellitus

Blood pressure

Quality of life

Abstract

Background: Vitamin D is one of the known lipoprotein hormones with metabolic properties. We aimed to determine the serum 25-hydroxy vitamin D concentration in overweight/obese subjects with Diabetes mellitus type Ⅱ (DM Ⅱ ) in association with systolic and diastolic Blood pressure and Quality of life compared with healthy participants. Methods: The current case-control study was carried out among 80 overweight/obese subjects with DM Ⅱ , and 77 healthy subjects matched by sex, age and body mass index (BMI). Serum 25-hydroxyvitamin D concentration was measured by ELISA method. In order to examine the Quality of life, the Persian version of SF36 questionnaire was used. Results: There was significant difference between diabetic and healthy subjects considering serum 25-hydroxyvitamin D concentration (p=0. 012). Serum 25-hydroxyvitamin D concentration was inversely correlated with diastolic Blood pressure (p=0. 02) and positively associated with physical function (p<0. 001), social function (p<0. 001) and general health (p<0. 001) components of Quality of life in diabetic subjects and physical health sub-scale (p=0. 004) in all participants. Conclusion: Serum 25-hydroxyvitamin D concentration was significantly lower in diabetic subjects in comparison with healthy controls. There was a significant reverse relationship between serum concentrations of 25-hydroxyvitamin D with diastolic Blood pressure and on the other hand, a significant positive relationship with physical function, social function and general health components and physical health subscale of Quality of life in participants with DM Ⅱ .

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APA: Copy

AGHAMOHAMMADZADEH, NASER, Dolatkhah, Neda, HASHEMIAN, MARYAM, SHAKOURI, SEYED KAZEM, & HASANPOUR, SAEED. (2020). The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects. CASPIAN JOURNAL OF INTERNAL MEDICINE, 11(3), 267-277. SID. https://sid.ir/paper/753755/en

Vancouver: Copy

AGHAMOHAMMADZADEH NASER, Dolatkhah Neda, HASHEMIAN MARYAM, SHAKOURI SEYED KAZEM, HASANPOUR SAEED. The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2020;11(3):267-277. Available from: https://sid.ir/paper/753755/en

IEEE: Copy

NASER AGHAMOHAMMADZADEH, Neda Dolatkhah, MARYAM HASHEMIAN, SEYED KAZEM SHAKOURI, and SAEED HASANPOUR, “The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 11, no. 3, pp. 267–277, 2020, [Online]. Available: https://sid.ir/paper/753755/en

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