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Information Journal Paper

Title

Super Infection of Cutaneous Leishmaniasis Caused by Leish-mania major and L. tropica to Crithidia fasciculata in Shiraz, Iran (Short Communication)

Pages

  2285-2292

Abstract

 Background: The aims of the current study were to determined present status of CL in Shiraz City, identify the causative species of Leishmania and conduct phylogenetic evaluations in detected parasites Methods: This study was conducted on 70 individuals with suspected CL that referred to the major health centers of Shiraz (Valfajr), Fars province, Iran, from Sep 2016 to Jul 2017. DNA was extracted from cultured Leishmania promastigotes and PCR-RFLP were performed using ITS1-rDNA gene. Results: Overall, 39 male (55. 70%) and 31 (44. 30%) female were found to be positive microscopically. All of direct examined positive samples were confirmed to be positive for Leishmania spp. DNA. Based upon the PCRRFLP patterns and phylogenetic analysis, 46 (65. 72%), 17 (24. 28%) and 7 (10%) isolates were clearly identified as L. major, L. tropica and C. fasciculata, respectively. Conclusion: The dominat detected species in Shiraz City was L. major and L. tropica, respectively. CL has high prevalence in Shiraz City; therefore, more studies on leishmaniasis in the natural vectors and also reservoirs infection in this region is exceedingly recommended. Skin leisons due to C. fasciculata, was described for the first time in Iran (Shiraz City).

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    APA: Copy

    Mirzapour, Aliyar, BADIRZADEH, ALIREZA, ASHRAFMANSOURI, Marzieh, BEHNIAFAR, HAMED, NOROUZI, MARYAM, AZIZI, HAKIM, BEHRAVAN, MAHMOODREZA, & SEYYED TABAEI, SEYYED JAVAD. (2019). Super Infection of Cutaneous Leishmaniasis Caused by Leish-mania major and L. tropica to Crithidia fasciculata in Shiraz, Iran (Short Communication). IRANIAN JOURNAL OF PUBLIC HEALTH, 48(12), 2285-2292. SID. https://sid.ir/paper/755147/en

    Vancouver: Copy

    Mirzapour Aliyar, BADIRZADEH ALIREZA, ASHRAFMANSOURI Marzieh, BEHNIAFAR HAMED, NOROUZI MARYAM, AZIZI HAKIM, BEHRAVAN MAHMOODREZA, SEYYED TABAEI SEYYED JAVAD. Super Infection of Cutaneous Leishmaniasis Caused by Leish-mania major and L. tropica to Crithidia fasciculata in Shiraz, Iran (Short Communication). IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2019;48(12):2285-2292. Available from: https://sid.ir/paper/755147/en

    IEEE: Copy

    Aliyar Mirzapour, ALIREZA BADIRZADEH, Marzieh ASHRAFMANSOURI, HAMED BEHNIAFAR, MARYAM NOROUZI, HAKIM AZIZI, MAHMOODREZA BEHRAVAN, and SEYYED JAVAD SEYYED TABAEI, “Super Infection of Cutaneous Leishmaniasis Caused by Leish-mania major and L. tropica to Crithidia fasciculata in Shiraz, Iran (Short Communication),” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 48, no. 12, pp. 2285–2292, 2019, [Online]. Available: https://sid.ir/paper/755147/en

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