Biochemical Assessment: Findings from 20 Years of the Tehran Lipid and Glucose Study

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HEDAYATI MEHDI; DANESHPOUR MARYAM SADAT; ZARKESH MARYAM; ZARIF YEGANEH MARJAN; SHEIKHOLESLAMI SARA; FAAM BITA; AZIZI FEREIDOUN

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Journal Paper

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Journal: International Journal of Endocrinology and Metabolism Year:2018 | Volume:16 | Issue:suppl 4 Page(s): 0-0

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Title

Biochemical Assessment: Findings from 20 Years of the Tehran Lipid and Glucose Study

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Keywords

TLGS

Iran

Biochemistry

Inflammatory Factors

Obesity

Metabolic Syndrome

Abstract

Context: The Tehran Lipid and Glucose Study (TLGS) is a community-based study to reveal the frequency of non-communicable diseases (NCDs) in Tehran’ s population. This research consists of two main parts, a cross-sectional study on the prevalence of cardiovascular risk factors and a 20-year-ongoing prospective cohort study, which was initiated in 1999 in several phases with an approximate duration of 3. 6 years, and is still ongoing. The aim of the present study is review the 20 year biochemical findings of the TLGS related to the NCDs in a large sample. Methods: All articles on biochemical assessments derived from the TLGS from the earliest publications (2002) until 30 January 2018 were reviewed for their findings on different risk factors of NCDs. Results: According to the TLGS findings high sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), homocysteine (Hcy), age, smoking, hypertension, and Obesity were the most important risk factors of cardiovascular diseases (CVD). It was illustrated that in subjects with abdominal Obesity, the hs-CRP and IL-6 serum levels were higher than in normal subjects. The most appropriate prognostic indexes and associations were for hs-CRP, IL-6, and Hcy with abdominal Obesity, waist circumference, WHtR, and wrist circumference, respectively. Previous studies have demonstrated a direct relationship between Obesity and serum levels of Inflammatory Factors. Conclusions: According to the results of TLGS, serum levels of biochemical risk factors such as hs-CRP, IL-6, and Hcy could be beneficial in early diagnosis and effective treatment of cardiovascular, Obesity and other metabolic diseases.

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APA: Copy

HEDAYATI, MEHDI, DANESHPOUR, MARYAM SADAT, ZARKESH, MARYAM, ZARIF YEGANEH, MARJAN, SHEIKHOLESLAMI, SARA, FAAM, BITA, & AZIZI, FEREIDOUN. (2018). Biochemical Assessment: Findings from 20 Years of the Tehran Lipid and Glucose Study. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 16(4 (Suppl.)), 0-0. SID. https://sid.ir/paper/756300/en

Vancouver: Copy

HEDAYATI MEHDI, DANESHPOUR MARYAM SADAT, ZARKESH MARYAM, ZARIF YEGANEH MARJAN, SHEIKHOLESLAMI SARA, FAAM BITA, AZIZI FEREIDOUN. Biochemical Assessment: Findings from 20 Years of the Tehran Lipid and Glucose Study. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2018;16(4 (Suppl.)):0-0. Available from: https://sid.ir/paper/756300/en

IEEE: Copy

MEHDI HEDAYATI, MARYAM SADAT DANESHPOUR, MARYAM ZARKESH, MARJAN ZARIF YEGANEH, SARA SHEIKHOLESLAMI, BITA FAAM, and FEREIDOUN AZIZI, “Biochemical Assessment: Findings from 20 Years of the Tehran Lipid and Glucose Study,” INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 16, no. 4 (Suppl.), pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/756300/en

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