The Preventive Role of Selenium in Inflammatory Response During Coronary Artery Bypass Graft Surgery: A Randomized, Controlled Clinical Trial

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SEDIGHINEJAD ABBAS; IMANTALAB VALI; MIRMANSOURI ALI; MOHAMMADZADEH JOURYABI ALI; NADERI NABI BAHRAM; KANANI GHOLAMREZA; ATRKARROUSHAN ZAHRA; BIAZAR GELAREH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Journal of Natural Pharmaceutical Products Year:2019 | Volume:14 | Issue:1 Page(s): 0-0

Download Full-Text

View:

149

Download:

124

Cites:

Information Journal Paper

Title

The Preventive Role of Selenium in Inflammatory Response During Coronary Artery Bypass Graft Surgery: A Randomized, Controlled Clinical Trial

Author(s)

Keywords

Coronary Artery Bypass Graft Surgery

Selenium

Inflammatory Response

Leukocytosis

Abstract

Background: Coronary Artery Bypass Graft Surgery (CABG) with cardiopulmonary bypass (CPB) triggers a profound systemic Inflammatory Response and sympathetic nervous system activation translated into post-operative adverse outcomes. Objectives: Thecurrent studyaimedat determiningwhether preparative use of Selenium could reduce the severity of inflammatory reaction to surgery. Methods: The current randomized, double-blind clinical trial was conducted at the Department of Cardiac Surgery of Dr. Heshmat Hospital; a referral center affiliated to Guilan University of Medical Sciences (GUMS), Rasht, Iran. From May 2015 to September 2015 one hundred and fourteen patientswhowere candidates for elective CABGwere randomly recruited to receive either an intravenous bolus of 600 g Se before induction of anesthesia in the group S (n = 56) or normal saline as placebo in the group C (n = 58). To measure white blood cells (WBC) serum levels, blood samples were collected preoperatively (T0) and three times after CPB initiation immediately after the end of CPB (T1), as well as 24 (T2) and 48 hours (T3) after surgery. Statistical tests including chi-square, the Kruskal-Wallis, and independent t tests, as well as repeated measurement ANOVA were used to analyze the data. Results: There was no significant difference between the two groups regarding the baseline characteristics (P = 0. 0512). There was no significant difference between the two groups in other four time points; T0 (P = 0. 0512), T1 (P = 0. 571), T2 (P = 0. 974), and T3 (P = 0. 215), although the trend of changes was statistically significant in each group (P = 0. 0001), the intergroup comparisons showed no significant changes (P = 0. 166). Conclusions: There was no strong evidence that a single-dose of Se could reduce inflammation following CABG surgery.

Cites

No record.

References

No record.

Cite

APA: Copy

SEDIGHINEJAD, ABBAS, IMANTALAB, VALI, MIRMANSOURI, ALI, MOHAMMADZADEH JOURYABI, ALI, NADERI NABI, BAHRAM, KANANI, GHOLAMREZA, ATRKARROUSHAN, ZAHRA, & BIAZAR, GELAREH. (2019). The Preventive Role of Selenium in Inflammatory Response During Coronary Artery Bypass Graft Surgery: A Randomized, Controlled Clinical Trial. JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS, 14(1), 0-0. SID. https://sid.ir/paper/757582/en

Vancouver: Copy

SEDIGHINEJAD ABBAS, IMANTALAB VALI, MIRMANSOURI ALI, MOHAMMADZADEH JOURYABI ALI, NADERI NABI BAHRAM, KANANI GHOLAMREZA, ATRKARROUSHAN ZAHRA, BIAZAR GELAREH. The Preventive Role of Selenium in Inflammatory Response During Coronary Artery Bypass Graft Surgery: A Randomized, Controlled Clinical Trial. JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS[Internet]. 2019;14(1):0-0. Available from: https://sid.ir/paper/757582/en

IEEE: Copy

ABBAS SEDIGHINEJAD, VALI IMANTALAB, ALI MIRMANSOURI, ALI MOHAMMADZADEH JOURYABI, BAHRAM NADERI NABI, GHOLAMREZA KANANI, ZAHRA ATRKARROUSHAN, and GELAREH BIAZAR, “The Preventive Role of Selenium in Inflammatory Response During Coronary Artery Bypass Graft Surgery: A Randomized, Controlled Clinical Trial,” JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS, vol. 14, no. 1, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/757582/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops