Serum concentration of hs-CRP in obese individuals with and without metabolic syndrome and its association with parameters of metabolic syndrome

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MIRHOSEINI MAHMOOD; Daemi Hamid; Masoom Babaiee Mahshid; ASADI SAMANI MAJID; Mirhoseini Leilaassadat; SEDEHI MORTEZA

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Journal: JOURNAL OF RENAL INJURY PREVENTION Year:2018 | Volume:7 | Issue:4 Page(s): 297-300

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Title

Serum concentration of hs-CRP in obese individuals with and without metabolic syndrome and its association with parameters of metabolic syndrome

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Keywords

Metabolic syndrome

Inflammatory markers

Metabolic parameters

Vitamin D

Abstract

Introduction: Serum level of high sensitivity C-reactive protein (hs-CRP), as an inflammatory marker, can play a role in development of Metabolic syndrome in obese individuals. Objectives: This study aimed to determine serum concentration of hs-CRP in obese patients with Metabolic syndrome and determine the association of this factor with factors involved in the progression of Metabolic syndrome. Patients and Methods: In this study, samples were selected by convenient method from obese patients, admitted to Kashani and Hajar hospitals (Shahrekord, Iran). First, based on NCEP-ATPIII-defined Metabolic syndrome, parameters of Metabolic syndrome and serum levels of Vitamin D were measured and a questionnaire containing demographics was completed for each participant. Accordingly, the samples (n=192) were divided into two identical groups; obese individuals without Metabolic syndrome (controls) and obese individuals with Metabolic syndrome (case group). Hs-CRP levels were measured in both groups. Results: Serum level of hs-CRP in the case group was 17. 58± 1. 40 μ g/mL and in the control group was 9. 04± 1. 26 μ g/mL, which was significantly higher in the case group than the control group (P < 0. 001). Serum concentration of hs-CRP in case and control subjects had a negative significant correlation with Vitamin D (P <0. 001), however, serum level of hs-CRP had no significant association with high density lipoprotein cholesterol (HDL-C), triglyceride (TG), fasting blood sugar (FBS), abdominal circumference, body mass index (BMI), and height (P > 0. 05). Conclusion: Hs-CRP can be used for prognosis and early detection of patients at risk of Metabolic syndrome.

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APA: Copy

MIRHOSEINI, MAHMOOD, Daemi, Hamid, Masoom Babaiee, Mahshid, ASADI SAMANI, MAJID, Mirhoseini, Leilaassadat, & SEDEHI, MORTEZA. (2018). Serum concentration of hs-CRP in obese individuals with and without metabolic syndrome and its association with parameters of metabolic syndrome. JOURNAL OF RENAL INJURY PREVENTION, 7(4), 297-300. SID. https://sid.ir/paper/758984/en

Vancouver: Copy

MIRHOSEINI MAHMOOD, Daemi Hamid, Masoom Babaiee Mahshid, ASADI SAMANI MAJID, Mirhoseini Leilaassadat, SEDEHI MORTEZA. Serum concentration of hs-CRP in obese individuals with and without metabolic syndrome and its association with parameters of metabolic syndrome. JOURNAL OF RENAL INJURY PREVENTION[Internet]. 2018;7(4):297-300. Available from: https://sid.ir/paper/758984/en

IEEE: Copy

MAHMOOD MIRHOSEINI, Hamid Daemi, Mahshid Masoom Babaiee, MAJID ASADI SAMANI, Leilaassadat Mirhoseini, and MORTEZA SEDEHI, “Serum concentration of hs-CRP in obese individuals with and without metabolic syndrome and its association with parameters of metabolic syndrome,” JOURNAL OF RENAL INJURY PREVENTION, vol. 7, no. 4, pp. 297–300, 2018, [Online]. Available: https://sid.ir/paper/758984/en

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