CLINICAL AND LABORATORY FINDINGS IN FAVISM

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ALAVI S.; NOZAD S.; HOSEINI M.

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Journal: Iranian Journal of Pediatrics Year:2005 | Volume:15 | Issue:1 Page(s): 13-20

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Title

CLINICAL AND LABORATORY FINDINGS IN FAVISM

Author(s)

ALAVI S. | NOZAD S. | HOSEINI M. | Issue Writer Certificate

Keywords

G6PD DEFICIENCYQ4

FAVISMQ3

HEMOLYTIC ANEMIAQ3

CLINICAL FEATURESQ4

LABORATORY FINDINGSQ3

Abstract

Background: FAVISM is an acute HEMOLYTIC ANEMIA which occurs in G6PD deficient individuals by ingestion of fava beans or inhalation of fava plant's pollens. Awareness of CLINICAL FEATURES and LABORATORY FINDINGS of this life threatening condition is first step in proper management and prevention of its complications. Methods: This retrospective descriptive study presents five years' data on hospitalized cases of FAVISM in Tehran. Data were collected from Mofid University Hospital for Children. We reviewed all in-patient charts for cases of FAVISM who presented with acute hemolytic crisis due to fava beans ingestion from March 1995 to March 2001. Data on demographic and CLINICAL FEATURES (e.g. pallor, dark urine and jaundice) and LABORATORY FINDINGS (e.g. serum concentrations of hemoglobin, creatinine, total and direct bilirubin, liver transaminases, reticulocyte count, direct Coombs test, qualitative G6PD measurement, and presence of hemoglobin, bilirubin, and urobilinogen in urine), positive family history of FAVISM and history about blood transfusion were evaluated. Findings: A total of 523 cases were recorded of whom 75.7% were male. The mean age of our patients was 27.7 months ± 46.4. Dark urine, pallor and jaundice were common manifestations of FAVISM (96.6%, 75.3%, and 70% respectively). Male gender was significantly associated with pallor and hemoglobin ≤7 gr/dL. (p = 0.04 and p = 0.001). Conclusions: Our findings about CLINICAL FEATURES and LABORATORY FINDINGS in FAVISM were compatible with those in literature. Our study suggests that parents are not reliable sources for differentiating of some CLINICAL FEATURES of FAVISM (e.g. paleness and jaundice).

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APA: Copy

ALAVI, S., NOZAD, S., & HOSEINI, M.. (2005). CLINICAL AND LABORATORY FINDINGS IN FAVISM. IRANIAN JOURNAL OF PEDIATRICS, 15(1), 13-20. SID. https://sid.ir/paper/75945/en

Vancouver: Copy

ALAVI S., NOZAD S., HOSEINI M.. CLINICAL AND LABORATORY FINDINGS IN FAVISM. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2005;15(1):13-20. Available from: https://sid.ir/paper/75945/en

IEEE: Copy

S. ALAVI, S. NOZAD, and M. HOSEINI, “CLINICAL AND LABORATORY FINDINGS IN FAVISM,” IRANIAN JOURNAL OF PEDIATRICS, vol. 15, no. 1, pp. 13–20, 2005, [Online]. Available: https://sid.ir/paper/75945/en

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