Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

144
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

293
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Chemical Composition and Biological Activity of Ferula aucheri Essential Oil

Pages

  21-31

Abstract

 Background and objectives: Antibiotics resistance and unpleasant side effects of AChE inhibitors have led to an increased interest in herbs as potential sources. Ferula aucheri (Syn: Dorema aucheri) an indigenous species of Ferula (Apiaceae) grows in Iran and is used as food and medicinal plant. The present study was aimed to identify the oil composition and evaluate antimicrobial and AChE inhibitory activity of flowering tops, fruits and roots. Methods: The chemical composition of the oils was recognized by GC and GC‐ MS. The antimicrobial effects were assessed on 12 microorganisms by disc diffusion and micro-well dilution methods and AChE inhibitory potential by a modified version of Ellman's method. Results: Sixty five compounds were identified from different organs and the notable characteristics have been high amounts of sesquiterpenes. Germacrene B (14. 96%) and β-caryophyllene (12. 87%) were distinguished as major components of flowering tops. Cis-dihydroagarofuran (9. 02%) and δ-cadinene (8. 28%) were identified as the remarkable constituents of fruit. δ-cadinene (18. 25%) and gurjunene (12. 62%) were detected from the roots by high content. All volatile oils exhibited lower MICs on Bacillus subtilis, Klebsiella pneumonia, Shigella dysenteriae, and Salmonella paratyphi-A serotype compared with gentamicin. Root and fruit oils were more effective than gentamicin against Escherichia coli and flowering tops oils proved lower MICs versus Staphylococcus aureus. Fruits and root oils showed weak potency for inhibiting AChE with IC50 values 554. 05± 4. 65 and 239. 69± 3. 5 μ g/mL, respectively and flowering tops exhibited moderate activity (179. 06± 4. 3 μ g/mL). Conclusion: The findings demonstrated that F. aucheri essential oils possessed antimicrobial activities with inhibition properties toward AchE.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    Ahmadi Koulaei, Sheyda, HADJIAKHOONDI, ABBAS, DELNAVAZI, MOHAMMAD REZA, TOFIGHI, ZAHRA, AJANI, YOUSEF, Kiashi, Fatemeh, & YASSA, NARGUESS. (2020). Chemical Composition and Biological Activity of Ferula aucheri Essential Oil. RESEARCH JOURNAL OF PHARMACOGNOSY, 7(2), 21-31. SID. https://sid.ir/paper/759475/en

    Vancouver: Copy

    Ahmadi Koulaei Sheyda, HADJIAKHOONDI ABBAS, DELNAVAZI MOHAMMAD REZA, TOFIGHI ZAHRA, AJANI YOUSEF, Kiashi Fatemeh, YASSA NARGUESS. Chemical Composition and Biological Activity of Ferula aucheri Essential Oil. RESEARCH JOURNAL OF PHARMACOGNOSY[Internet]. 2020;7(2):21-31. Available from: https://sid.ir/paper/759475/en

    IEEE: Copy

    Sheyda Ahmadi Koulaei, ABBAS HADJIAKHOONDI, MOHAMMAD REZA DELNAVAZI, ZAHRA TOFIGHI, YOUSEF AJANI, Fatemeh Kiashi, and NARGUESS YASSA, “Chemical Composition and Biological Activity of Ferula aucheri Essential Oil,” RESEARCH JOURNAL OF PHARMACOGNOSY, vol. 7, no. 2, pp. 21–31, 2020, [Online]. Available: https://sid.ir/paper/759475/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top