PREVALENCE OF CONGENITAL HEART DEFECTS IN CHILDREN WITH DOWN’S SYNDROME IN IMAM KHOMEINI HOSPITAL, TEHRAN

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AKBARI ASBAGH PARVIN; GHASEMI M.; ZAMANI ALI

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Journal: Iranian Journal of Pediatrics Year:2007 | Volume:17 | Issue:1 (SUPPLEMENT) Page(s): 95-100

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Information Journal Paper

Title

PREVALENCE OF CONGENITAL HEART DEFECTS IN CHILDREN WITH DOWN’S SYNDROME IN IMAM KHOMEINI HOSPITAL, TEHRAN

Author(s)

AKBARI ASBAGH PARVIN | GHASEMI M. | ZAMANI ALI | Issue Writer Certificate

Keywords

DOWN’S SYNDROMEQ2

CONGENITAL HEART DEFECTSQ3

CARDIAC ANOMALIESQ3

ECHOCARDIOGRAPHYQ3

CHROMOSOMAL ABNORMALITIESQ3

Abstract

Background: The aim of this study was to investigate the prevalence of CONGENITAL HEART DEFECTS in children with Down's syndrome in Imam Khomeini Hospital in a period of 2 years (2001-2002).Methods: Based on their medical files and echocardiographies, 32 patients with DOWN’S SYNDROME were evaluated during study. Findings: The cytogenetic analysis in these patients (19 males and 13 females) revealed that 29 cases (90.7%) had trisomy 21, 2 cases (6.2%) had translocation and only one case (3.1%) was mosaic. Family history for heart diseases was positive in 2 patients (6.2%). The findings of ECHOCARDIOGRAPHY were as follow: endocardial cushion defect (ECD) in 16 cases (50%), ventricular septal defect (VSD) in 7 cases (21.8%), atrial septal defect (ASD) in 6 cases (18.7%), tetralogy of Fallot (TOF) in 2 cases (6.2%), patent ductus arteriousus (PDA) in one case (3.1%).Conclusions: The diagnosis of CONGENITAL HEART DEFECTS in children with DOWN’S SYNDROME is crucial because treating them in due course results in dramatical decrease in the mortality and morbidity rates of these patients.

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APA: Copy

AKBARI ASBAGH, PARVIN, GHASEMI, M., & ZAMANI, ALI. (2007). PREVALENCE OF CONGENITAL HEART DEFECTS IN CHILDREN WITH DOWN’S SYNDROME IN IMAM KHOMEINI HOSPITAL, TEHRAN. IRANIAN JOURNAL OF PEDIATRICS, 17(1 (SUPPLEMENT)), 95-100. SID. https://sid.ir/paper/76049/en

Vancouver: Copy

AKBARI ASBAGH PARVIN, GHASEMI M., ZAMANI ALI. PREVALENCE OF CONGENITAL HEART DEFECTS IN CHILDREN WITH DOWN’S SYNDROME IN IMAM KHOMEINI HOSPITAL, TEHRAN. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2007;17(1 (SUPPLEMENT)):95-100. Available from: https://sid.ir/paper/76049/en

IEEE: Copy

PARVIN AKBARI ASBAGH, M. GHASEMI, and ALI ZAMANI, “PREVALENCE OF CONGENITAL HEART DEFECTS IN CHILDREN WITH DOWN’S SYNDROME IN IMAM KHOMEINI HOSPITAL, TEHRAN,” IRANIAN JOURNAL OF PEDIATRICS, vol. 17, no. 1 (SUPPLEMENT), pp. 95–100, 2007, [Online]. Available: https://sid.ir/paper/76049/en

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