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Title

REVIEW OF DEMOGRAPHIC CHARACTERISTICS, CLINAL SIGNS AND SYMPTOMS, COMPLICATIONS, TREATMENT, AND RESULTS OF FOLLOW-UP IN HENOCH- SCHOENLEIN PURPURA PATIENTS HOSPITALIZED IN CHILDREN'S MEDICAL CENTER, TEHRAN, MARCH 1986 TO FEBRUARY 2001

Pages

  69-76

Abstract

 Henoch Schoenlein PURPURA (HSP) is a VASCULITIS of small vessels (post capillaries, arteriols and venols) with unknown etiology. We studied the disease in 134 children, who were admitted to the Children's Medical Center in Tehran from March 1986 to February 2001.The mean age of patients was 7.259 (SD - 2.982).The male to female ratio was 67%. Maximal seasonal occurrence was in autumn and spring.A history of infectious disease prior to HSP, mostly URI, was positive in 52% of cases.Most frequently encountered signs and symptoms were: Skin manifestation in 94%, arthralgia and arthritis in 79.85%, gasterointestinal involvement in 72.38%, renal involvement in 38.8%.Laboratory findings: Anemia in 52%, increased ESR and positive CRP in 64%, serum 19A was abnormal in 12.19% of patients.Culture of pharynx was positive in 19.4% of samples and ASOT>625 in 13.4%. There was a positive history of drug administration prior to admission in 40.30%. BUN and serum creatinine was increased in 14.2%.Complications occurred in 30.59% of cases, 14.63% had renal problems.We found hematuria in 36.11%, proteinuria in 33% of cases and severe gastrointestinal pain and hemorrhage in one case.About 35.8% of our patients were managed conservatively, and 16.4% were treated with NSAIDs, 53.7% with corticosteroids, 14.2% with cytotoxic drugs, and 7.5% received methylprednisolone and cyclophosphamide pulse.This study being conducted in hospitalized patients, did not contain mild and moderate cases of HSP, who are normally managed as outpatients.In order to get more precise results, we suggest to study cases who are visited in outpatient clinics.

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    APA: Copy

    MORADINEZHAD, MOHAMMAD HASAN. (2003). REVIEW OF DEMOGRAPHIC CHARACTERISTICS, CLINAL SIGNS AND SYMPTOMS, COMPLICATIONS, TREATMENT, AND RESULTS OF FOLLOW-UP IN HENOCH- SCHOENLEIN PURPURA PATIENTS HOSPITALIZED IN CHILDREN'S MEDICAL CENTER, TEHRAN, MARCH 1986 TO FEBRUARY 2001. IRANIAN JOURNAL OF PEDIATRICS, 13(1), 69-76. SID. https://sid.ir/paper/76074/en

    Vancouver: Copy

    MORADINEZHAD MOHAMMAD HASAN. REVIEW OF DEMOGRAPHIC CHARACTERISTICS, CLINAL SIGNS AND SYMPTOMS, COMPLICATIONS, TREATMENT, AND RESULTS OF FOLLOW-UP IN HENOCH- SCHOENLEIN PURPURA PATIENTS HOSPITALIZED IN CHILDREN'S MEDICAL CENTER, TEHRAN, MARCH 1986 TO FEBRUARY 2001. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2003;13(1):69-76. Available from: https://sid.ir/paper/76074/en

    IEEE: Copy

    MOHAMMAD HASAN MORADINEZHAD, “REVIEW OF DEMOGRAPHIC CHARACTERISTICS, CLINAL SIGNS AND SYMPTOMS, COMPLICATIONS, TREATMENT, AND RESULTS OF FOLLOW-UP IN HENOCH- SCHOENLEIN PURPURA PATIENTS HOSPITALIZED IN CHILDREN'S MEDICAL CENTER, TEHRAN, MARCH 1986 TO FEBRUARY 2001,” IRANIAN JOURNAL OF PEDIATRICS, vol. 13, no. 1, pp. 69–76, 2003, [Online]. Available: https://sid.ir/paper/76074/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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