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Information Journal Paper

Title

Comparing the Quality of Life in Patients with Multiple Sclerosis Consuming Fingolimod and Cinnovex

Pages

  151-160

Keywords

Multiple Sclerosis (MS) 
Quality of Life (QoL) 

Abstract

 Background: Multiple Sclerosis (MS) is a chronic demyelinating, inflammatory, and degenerative disease of the central nervous system. MS gradually limits and deteriorates the patients’ quality of life. Objectives: This study aimed to evaluate and compare the quality of life in patients with MS consuming Fingolimod and Cinnovex. Materials & Methods: In an analytical cross-sectional study, 106 patients with Relapsing-Remitting MS (RRMS) referred to specialized neurology clinics of Guilan University of Medical Sciences were selected for the study using a convenience sampling method (52 patients consuming Fingolimod and 54 patients consuming Cinnovex). Then, we collected their demographic information and medical profile. The patients were assessed by the Hamburg quality of life questionnaire in MS. The obtained data were analyzed in SPSS V. 22 using the Chi-square test, independent t-test, Mann-Whitney U, One-Way and multivariate analysis of covariance. Results: There was a significant difference between the two groups in terms of age, number of attacks in the last 6 months, and educational level (P<0. 05). After controlling confounding variables, it was found that consumers of Fingolimod had a better quality of life. At the subscales level, this difference was significant only in the mood dimension (F=6. 931, P=0. 011, η =0. 12). Conclusion: Patients consuming Fingolimod reported a better quality of life compared to consumers of Cinnovex. This improvement was mainly found in mood scores.

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    Cite

    APA: Copy

    SABERI, ALIA, HATAMIAN, HAMIDREZA, GHAYEGHRAN, AMIRREZA, Mollahosseni, Fatemeh, Aghayari Sheikh Neshin, Saeideh, Noroozi Guilandehi, Sama, REZAEI, SAJJAD, & Shafaei, Fatemeh. (2019). Comparing the Quality of Life in Patients with Multiple Sclerosis Consuming Fingolimod and Cinnovex. CASPIAN JOURNAL OF NEUROLOGICAL SCIENCES, 5(4 (19)), 151-160. SID. https://sid.ir/paper/761844/en

    Vancouver: Copy

    SABERI ALIA, HATAMIAN HAMIDREZA, GHAYEGHRAN AMIRREZA, Mollahosseni Fatemeh, Aghayari Sheikh Neshin Saeideh, Noroozi Guilandehi Sama, REZAEI SAJJAD, Shafaei Fatemeh. Comparing the Quality of Life in Patients with Multiple Sclerosis Consuming Fingolimod and Cinnovex. CASPIAN JOURNAL OF NEUROLOGICAL SCIENCES[Internet]. 2019;5(4 (19)):151-160. Available from: https://sid.ir/paper/761844/en

    IEEE: Copy

    ALIA SABERI, HAMIDREZA HATAMIAN, AMIRREZA GHAYEGHRAN, Fatemeh Mollahosseni, Saeideh Aghayari Sheikh Neshin, Sama Noroozi Guilandehi, SAJJAD REZAEI, and Fatemeh Shafaei, “Comparing the Quality of Life in Patients with Multiple Sclerosis Consuming Fingolimod and Cinnovex,” CASPIAN JOURNAL OF NEUROLOGICAL SCIENCES, vol. 5, no. 4 (19), pp. 151–160, 2019, [Online]. Available: https://sid.ir/paper/761844/en

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