The Effect of Eight-Week Aerobic Exercises on Vascular Cellular Adhesion Molecule-1, Intracellular Adhesion Molecule and Body Composition of Addicts Treated with Methadone

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Zibandepoor Mahboobeh; TAGHIAN FARZANEH; FARAMARZI MOHAMMAD

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Journal: Journal of Rehabilitation Sciences and Research Year:2019 | Volume:6 | Issue:3 Page(s): 137-142

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Title

The Effect of Eight-Week Aerobic Exercises on Vascular Cellular Adhesion Molecule-1, Intracellular Adhesion Molecule and Body Composition of Addicts Treated with Methadone

Author(s)

Zibandepoor Mahboobeh | TAGHIAN FARZANEH | FARAMARZI MOHAMMAD | Issue Writer Certificate

Keywords

Aerobic exercises Addiction Opioids Cell adhesion molecules

Abstract

Background: Drug consumption and addiction lead to serious cardiovascular diseases as well as inflammation. Cellular adhesion molecules are glycoproteins that mediate a leukocyte reaction to inflammation. This study aims to determine the effect of aerobic exercises on some cardiovascular factors in addicts treated with methadone. Methods: This is a semi-experimental research. To conduct this research, 30 male addicted patients treated with methadone with a mean age of 33. 53± 15. 42 years, 70. 06± 15. 42kg weight and 174. 8± 5. 69cm were selected after medical screening and randomly divided into experimental (n=16) and control (n=16) groups. First, the height, weight and body mass index (BMI) of participants in both groups were measured. Blood samples were taken from the subjects in order to measure the intercellular adhesion molecules 1 (sICAM) and cellular vascular adhesion 1 (sVCAM) in serum. The experimental group had an aerobic exercise program including use of a treadmill with a 40 to 50% maximum heart rate in the beginning and then, a 70 to 80% maximum heart rate. The control group had only a follow-up. After 8 weeks, all variables were measured in both groups. Correlated t-test and independent t-test were used for intragroup and intergroup comparisons (P<0. 05). Results: Results showed that after 8 weeks aerobic exercises, there was no significant difference in ICAM-1 (P=0. 397), VCAM-1 (P=0. 521), and BMI (P=0. 223). Conclusion: Although 8-weeks aerobic exercise was not effective and sufficient for BMI, ICAM-1 and VCAM-1 indicators of the addicts treated with methadone, but it reduced ICAM-1 and VCAM-1 in the exercise group

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APA: Copy

Zibandepoor, Mahboobeh, TAGHIAN, FARZANEH, & FARAMARZI, MOHAMMAD. (2019). The Effect of Eight-Week Aerobic Exercises on Vascular Cellular Adhesion Molecule-1, Intracellular Adhesion Molecule and Body Composition of Addicts Treated with Methadone. JOURNALS OF REHABILITATION SCIENCES AND RESEARCH, 6(3), 137-142. SID. https://sid.ir/paper/762976/en

Vancouver: Copy

Zibandepoor Mahboobeh, TAGHIAN FARZANEH, FARAMARZI MOHAMMAD. The Effect of Eight-Week Aerobic Exercises on Vascular Cellular Adhesion Molecule-1, Intracellular Adhesion Molecule and Body Composition of Addicts Treated with Methadone. JOURNALS OF REHABILITATION SCIENCES AND RESEARCH[Internet]. 2019;6(3):137-142. Available from: https://sid.ir/paper/762976/en

IEEE: Copy

Mahboobeh Zibandepoor, FARZANEH TAGHIAN, and MOHAMMAD FARAMARZI, “The Effect of Eight-Week Aerobic Exercises on Vascular Cellular Adhesion Molecule-1, Intracellular Adhesion Molecule and Body Composition of Addicts Treated with Methadone,” JOURNALS OF REHABILITATION SCIENCES AND RESEARCH, vol. 6, no. 3, pp. 137–142, 2019, [Online]. Available: https://sid.ir/paper/762976/en

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