THE EFFECT OF CHRONIC L-CARNITNE SUPPLEMENTATION ON PLASMA GLUCOSE AND LACTATE DURING EXERCISE

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IZADI M.; AGHDAMI A.; KHOURSHIDI D.; AHMADI S.; DOUALI H.; KIANI FATEMEH

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Title

THE EFFECT OF CHRONIC L-CARNITNE SUPPLEMENTATION ON PLASMA GLUCOSE AND LACTATE DURING EXERCISE

Author(s)

Keywords

L-CARNITINEQ2

GLUCOSEQ2

LACTATEQ2

METABOLISMQ2

AEROBIC EXERCISEQ2

Abstract

Background and Aim: In skeletal muscle, carnitine plays an essential role in the translocation of long-chain fatty-acids into the mitochondrial matrix for subsequent beta-oxidation. Despite an abundance of literature describing the basic mechanisms of action of L-CARNITINE METABOLISM, there remains some uncertainty regarding the effects of oral L-CARNITINE supplementation on METABOLISM and exercise performance in normal subjects. This study examined the effects of chronic L-CARNITINE supplementation on GLUCOSE and LACTATE concentration, heart rate and aerobic capacity during submaximal cycling. Material and Methods: Thirty healthy and male students cycled for 20 min at 70% VO2 max before and after 3 weeks (3g daily) L-CARNITINE (experimental) and placebo (control) supplementation. Blood samples were taken immediately after each exercise for the purpose of calculation plasma GLUCOSE and LACTATE concentration, LACTATE dehydrogenase activity (LDH). A two-way repeated measure ANOVA was used to determine significant differences between the two groups (p<0.05). Result: The finding of our study showed that L-CARNITINE supplementation had no influence on plasma GLUCOSE and LACTATE. Also rest and rest heart rate, VO2 max and LDH activity was equal in pre and posttests (p<0.05). All variables were unaffected in the control trial. Conclusion: Three weeks L-CARNITINE supplementation had no effect on substrate and carbohydrate METABOLISM. Also, L-CARNITINE supplementation would be unlikely to be associated with the enhanced exercise performance.

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APA: Copy

IZADI, M., AGHDAMI, A., KHOURSHIDI, D., AHMADI, S., DOUALI, H., & KIANI, FATEMEH. (2009). THE EFFECT OF CHRONIC L-CARNITNE SUPPLEMENTATION ON PLASMA GLUCOSE AND LACTATE DURING EXERCISE. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 13(4 (SERIAL NUMBER 50)), 16-22. SID. https://sid.ir/paper/76339/en

Vancouver: Copy

IZADI M., AGHDAMI A., KHOURSHIDI D., AHMADI S., DOUALI H., KIANI FATEMEH. THE EFFECT OF CHRONIC L-CARNITNE SUPPLEMENTATION ON PLASMA GLUCOSE AND LACTATE DURING EXERCISE. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;13(4 (SERIAL NUMBER 50)):16-22. Available from: https://sid.ir/paper/76339/en

IEEE: Copy

M. IZADI, A. AGHDAMI, D. KHOURSHIDI, S. AHMADI, H. DOUALI, and FATEMEH KIANI, “THE EFFECT OF CHRONIC L-CARNITNE SUPPLEMENTATION ON PLASMA GLUCOSE AND LACTATE DURING EXERCISE,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 4 (SERIAL NUMBER 50), pp. 16–22, 2009, [Online]. Available: https://sid.ir/paper/76339/en

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