مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

160
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

108
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Comparison of the Effects of Combination of Turmeric, Ginger and Cinnamon Hydroalcoholic Extracts with Metformin on Body Weight, Glycemic Control, Inflammation, Oxidative Stress and Pancreatic Histopatalogical Changes in Diabetic Rat

Pages

  61-68

Abstract

 Background: Type 2 diabetes is a progressive disease. This study Compared effects of combination of Turmeric, Ginger and Cinnamon hydroalcoholic extracts with Metformin on body weight, glycemic control, inflammation, oxidative stress and pancreatic histopatalogical changes in diabetic rat. Methods: Rats were randomly assigned to four groups of 13 animals. Diabetes was induced by a single injection of streptozotocin (STZ, 65 mg/kg) and nicotinamide (110 mg/kg, 15 min before STZ injection). Normal control (NC) and diabetic control (DC) rats received 1 mL of distilled water and two other diabetic groups received either 300 mg/kg (HETGCC) or 100 mg/kg Metformin for 6 weeks. Results: HETGCC and Metformin significantly decreased serum glucose, glycated hemoglobin (HbA1c), Homeostatic Model Assessment for Insulin Resistance (HOMA index), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and malondialdehyde (MDA) levels and significantly increased high-density lipoprotein cholesterol (HDL-C) concentrations compared to DC group. A significant increase in the number and diameter of the islets of Langerhans (IL) and body weight was seen in HETGCC group compared to DC rats and a significant increase in quantitative insulin sensitivity check index (QUICKI) was observed in Metformin treated group. HETGCC and Metformin did not have significant effects on hsCRP, insulin and triglyceride (TG) concentrations in diabetic rats. Conclusion: HETGCC was shown to reduce the risk of diabetes and improve complications associated with diabetes such as hyperglycemia, dyslipidemia, oxidative stress, inflammation, histopathological statue of islets of Langerhans and weight loss in T2D patients.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    MOOSAVI, LEILA, MAZLOOM, ZOHRE, MOKHTARI, MARAL, Mohammadi Sartang, Mohsen, & Mahmoodi, Marzieh. (2020). Comparison of the Effects of Combination of Turmeric, Ginger and Cinnamon Hydroalcoholic Extracts with Metformin on Body Weight, Glycemic Control, Inflammation, Oxidative Stress and Pancreatic Histopatalogical Changes in Diabetic Rat. INTERNATIONAL JOURNAL OF NUTRITION SCIENCES, 5(2), 61-68. SID. https://sid.ir/paper/763691/en

    Vancouver: Copy

    MOOSAVI LEILA, MAZLOOM ZOHRE, MOKHTARI MARAL, Mohammadi Sartang Mohsen, Mahmoodi Marzieh. Comparison of the Effects of Combination of Turmeric, Ginger and Cinnamon Hydroalcoholic Extracts with Metformin on Body Weight, Glycemic Control, Inflammation, Oxidative Stress and Pancreatic Histopatalogical Changes in Diabetic Rat. INTERNATIONAL JOURNAL OF NUTRITION SCIENCES[Internet]. 2020;5(2):61-68. Available from: https://sid.ir/paper/763691/en

    IEEE: Copy

    LEILA MOOSAVI, ZOHRE MAZLOOM, MARAL MOKHTARI, Mohsen Mohammadi Sartang, and Marzieh Mahmoodi, “Comparison of the Effects of Combination of Turmeric, Ginger and Cinnamon Hydroalcoholic Extracts with Metformin on Body Weight, Glycemic Control, Inflammation, Oxidative Stress and Pancreatic Histopatalogical Changes in Diabetic Rat,” INTERNATIONAL JOURNAL OF NUTRITION SCIENCES, vol. 5, no. 2, pp. 61–68, 2020, [Online]. Available: https://sid.ir/paper/763691/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button