Protective effect of vitamin D against rats’ mandibular osteoporosis induced by corticosteroids and gamma rays

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Elkady a.a.; Kazem H.H.; Elgendy E.A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Radiation Research Year:2020 | Volume:18 | Issue:1 Page(s): 125-131

Download Full-Text

View:

158

Download:

221

Cites:

Information Journal Paper

Title

Protective effect of vitamin D against rats’ mandibular osteoporosis induced by corticosteroids and gamma rays

Author(s)

Elkady a.a. | Kazem H.H. | Elgendy E.A. | Issue Writer Certificate

Keywords

Osteoporosis y-rays

Epirelefan

Vit D

Rats

Abstract

Background: Osteoporosis is a progressive systematic skeletal illness characterized by low bone mineral density (BMD), deterioration of microarchitecture of bone tissues and susceptibility to fracture caused by bone resorption. The study investigates the possible role of Alfacalcidol; vitamin D (Vit D) to mitigate osteoporosis induced by corticosteroid and γ-rays in Rats. Materials and Methods: Eighty Sprague-Dawley Rats were divided equally into eight groups: Control group (1 ml olive oil orally), Epirelefan group (7mg/kg sc), Vit D group (20, 000 IU/kg orally), Vit D plus Epirelefan group, Vit D plus γ-rays (8 Gy) group, Epirelefan plus γ-rays group, Vit D plus Epirelefan plus γ-rays group and γ-rays groups. Results: In Epirelefan group, mandible bone has small cavities, micro fissures, thinning and decrease in the number of trabecular, which may appear rod-like and concave beside increase marrow cavities. In Epirelefan + γ-rays group, the lesions were more severe with increasing osteoclast and alteration of serum calcium, phosphate and alkaline phosphatase. The administration of Vit D before corticosteroid injection and pre γ-rays-irradiation has significantly reduced mandibular damage. Conclusion: Vit D could be efficient in mitigating osteoporosis occurred by corticosteroid and γ-rays in rat model.

Cites

Osteoporosis Risk Prediction Using Data Mining Algorithms

References

No record.

Cite

APA: Copy

Elkady, a.a., Kazem, H.H., & Elgendy, E.A.. (2020). Protective effect of vitamin D against rats’ mandibular osteoporosis induced by corticosteroids and gamma rays. INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 18(1), 125-131. SID. https://sid.ir/paper/764248/en

Vancouver: Copy

Elkady a.a., Kazem H.H., Elgendy E.A.. Protective effect of vitamin D against rats’ mandibular osteoporosis induced by corticosteroids and gamma rays. INTERNATIONAL JOURNAL OF RADIATION RESEARCH[Internet]. 2020;18(1):125-131. Available from: https://sid.ir/paper/764248/en

IEEE: Copy

a.a. Elkady, H.H. Kazem, and E.A. Elgendy, “Protective effect of vitamin D against rats’ mandibular osteoporosis induced by corticosteroids and gamma rays,” INTERNATIONAL JOURNAL OF RADIATION RESEARCH, vol. 18, no. 1, pp. 125–131, 2020, [Online]. Available: https://sid.ir/paper/764248/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops