EVALUATION OF ASTAXANTHIN EFFECTS ON THE SURVIVAL AND PROLIFERATION OF HUMAN ADIPOSE DERIVED STEM CELLS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHASEMI N.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

650

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF ASTAXANTHIN EFFECTS ON THE SURVIVAL AND PROLIFERATION OF HUMAN ADIPOSE DERIVED STEM CELLS

Author(s)

GHASEMI N. | Issue Writer Certificate

Keywords

ASTAXANTHINQ1

CELL PROLIFERATIONQ2

CELL SURVIVALQ1

Abstract

Background and Aim: In order to enhance in vivo stem cell viability and considering similar anti-inflammatory and anti-apoptotic effects of human adipose derived stem cells (hADSCs) and ASTAXANTHIN (AST) and their ability to cross the blood-brain barrier, we investigated the effects of (AST) on hADSCs proliferation and viability to provide a supplement for cell based therapy in MS patients.Materials and methods: After isolation of hADSCs and assessment of CD markers, they were cultured in DMEM-F12 medium in the presence of AST at various concentrations (1, 5, and 10 ng/ml) for 72 h. Finally, we assessed CELL PROLIFERATION and cell viability by MTT and Tryphan Blue methods.Results: The results revealed that a high percentage of hADSCs expressed CD90 and CD44 markers and a low percentage of them expressed hematopoietic cell markers. In addition, in the group cultured in the presence of 5 ng/ml AST the mean percentage of cell viability increased significantly compared to other groups (p = 0.04). Tryphan Blue results also revealed significant effect of AST on stem CELL PROLIFERATION and culture of these cells in the presence of 5 ng/ml of AST, led to significant increase in the mean percentage of cell count compared to the results of the control group (p = 0.03).Conclusion: ASTAXANTHIN can increase hADSCs proliferation and survival and this agent can be used in the cell-based therapies in MS patients.

Cites

No record.

References

No record.

Cite

APA: Copy

GHASEMI, N.. (2018). EVALUATION OF ASTAXANTHIN EFFECTS ON THE SURVIVAL AND PROLIFERATION OF HUMAN ADIPOSE DERIVED STEM CELLS. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 22(5 ), 84-92. SID. https://sid.ir/paper/76591/en

Vancouver: Copy

GHASEMI N.. EVALUATION OF ASTAXANTHIN EFFECTS ON THE SURVIVAL AND PROLIFERATION OF HUMAN ADIPOSE DERIVED STEM CELLS. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;22(5 ):84-92. Available from: https://sid.ir/paper/76591/en

IEEE: Copy

N. GHASEMI, “EVALUATION OF ASTAXANTHIN EFFECTS ON THE SURVIVAL AND PROLIFERATION OF HUMAN ADIPOSE DERIVED STEM CELLS,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 22, no. 5 , pp. 84–92, 2018, [Online]. Available: https://sid.ir/paper/76591/en

Related Journal Papers